病毒性肝炎患者血清转铁蛋白临床价值再评价

详细信息

Revaluate the clinical significance of serum transferrin changes in patients with hepatitis

摘要: 进一步评价血清转铁蛋白变化在病毒性肝炎患者中的临床意义。对 16 1例不同临床类型的病毒性肝炎患者进行血清转铁蛋白检测 ,同时检测凝血酶原时间、血清总胆红素。除急性肝炎患者外 ,各组血清转铁蛋白值与对照组比较有显著性差异 ,慢性重型肝炎患者血清转铁蛋白下降较肝硬化、慢性肝炎 (重度 )均明显 ,比较有显著性差异 (P <0 0 0 1,P <0 0 1) ,血清转铁蛋白与凝血酶原活动度呈正相关 ,而与血清总胆红素无明显相关性。血清转铁蛋白可以作为鉴别急性、慢性肝炎的指标之一 ,血清转铁蛋白随肝实质损害的加重而降低可以作为反映肝细胞坏死程度较敏感可靠的指标 ,对重型肝炎的预后判断有价值。
- 转铁蛋白 /
- 病毒性肝炎
Abstract: To revaluate the clinical significance of serum transferrin changes in patients with hepatitis. Serum transferrin, prosthrombin and total serum bilirubin were detected in 161 patients with different types of hepatitis. There were significant difference in serum transferrin compared different types of hepatitis with control group, except for the case of acute hepatitis. The levels of serum transferrin were: chronic severe hepatitis
- transferrin /
- hepatitis

[1] 盛蓝明, 吴瑞庭, 孙家强.血清前白蛋白质、转铁蛋白和抗胰蛋白酶检测及其在病毒性肝炎中的临床意义[J].中华传染病杂志, 1988, 6 (2) ∶89-91.

[2] BonkovskyHL , BannerBF , RothmanAL .Ironandchronicviralhepati tis[J].Hepatology, 1997, 25 (3) ∶759-68.

[3] DiBisceglieAM .AxiotisCA , HoofnagleJH , etal.Measurementsofironstatusinpatientswithchronichepatitis[J].Gastroenterology, 1992, 102 (6) ∶2108-13.

[4]高艳琴, 吕屏, 汪经.慢性肝炎患者血清转铁蛋白含量变化与肝细胞损害程度的关系[J].上海医科大学学报, 1995, 22 (4) ∶269-271.

[5]曹治宸, 白玉, 杨学农, 等.乙型肝炎肝损伤中铁代谢异常的研究[J].中华肝脏病杂志, 2001, 9 (2) ∶37-39.

本文二维码

用微信扫码二维码

分享至好友和朋友圈