乙型肝炎患者血清HBVDNA负荷与其肝功能及肝组织损害的关系研究

柳龙根; 翟德芳; 刘健红; 钱梅云; 方国平

乙型肝炎患者血清HBVDNA负荷与其肝功能及肝组织损害的关系研究

基金项目:

常州市科学技术局资助 (常科发 [2 0 0 2 ] 69号 (1 0 ) )；

详细信息

中图分类号: R512.62
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出版历程
- 出版日期: 2005-01-20

Researeh on the correlation between the contents of serum HBV DNA and liver function and liver tissue injury in hepatitis B patients.

Research funding:

摘要

摘要: 探讨乙肝患者血清HBVDNA含量与其肝功能及肝组织损害的关系。检测 380例未经治疗的乙肝患者血清HBVDNA、肝功能 ,其中 71例进行了肝活检。乙肝患者血清HBVDNA含量与其病情的严重程度不一致 ;临床各型乙肝中HBVDNA阳性组与阴性组间ALT、TBil均无显著差异 (P >0 0 5 ) ;肝组织炎症分级Gi～G4和纤维化分期S1～S4各组间HBVDNA值均无明显差异 (P >0 0 5 )。乙肝患者血清HBVDNA含量不能反映其病情的临床严重程度 ,与肝组织炎症和纤维化程度无关
- 乙型肝炎 /
- HBVDNA /
- 肝功能 /
- 肝组织
Abstract: To evaluate the serum HBV DNA level in hepatitis B and its relation with liver function and liver tissue injury.380 untreated patients with hepatitis B were selected and their serum HBVDNA level and liver function were detected, and among them 71 cases received liver biopsy.Serum HBVDNA level disaccord with state of their illness;serum ALT and TBil in those HBVDNA (+) and HBVDNA (-) have no difference (P>0.05) ;HAI scores have no relation with serum HBVDNA level (P>0.05) .Serum HBVDNA level cannot reflect the state of hepatitis illness, and no correlation with inflammation and fibrosis in liver.
- Hepatitis B /
- HBVDNA /
- Liver function Liver tissue /

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参考文献(7)

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