中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

中草药致肝小静脉闭塞病11例临床分析

李杨 许建明

引用本文:
Citation:

中草药致肝小静脉闭塞病11例临床分析

详细信息
  • 中图分类号: R595.3

Clinical analysis of 11 cases of hepatic veno-occlusive disease caused by Chinese herbal medicine

  • 摘要: 目的评估各种常规临床检测方法对中草药所致肝小静脉闭塞病(HVOD)的诊断价值,并探寻评价疾病转归及预后的方法。方法采用回顾性研究方法,分析我院近3年间服用中草药所致11例HVOD的临床表现、生化指标和影像学特点。结果所有患者均有明确用药史,7例患者服用土三七,2例患者服用雷公藤,2例患者服用不明中草药,CT对HVOD的诊断有重要意义,死亡4例患者均为重型患者。结论我国肝小静脉闭塞病的诊断应重视患者用药史,HVOD患者的疾病分型对病情评估有重要意义。

     

  • [1]Chen Z, Huo JR.Hepatic veno-occlusive disease associated with toxicity of pyrrolizidine alkaloids in herbal preparations[J].Neth J Med, 2010, 68 (6) :252-260.
    [2]Cefalo MG, Maurizi P, Arlotta A, et al.Hepatic veno-occlusive disease:a chemotherapy-related toxicity in children with malignancies[J].Paediatr Drugs, 2010, 12 (5) :277-284.
    [3]吴国琳, 余国友, 陈玖.中药土三七致肝小静脉闭塞病临床分析[J].中国中药杂志, 2008, 33 (20) :2402-2404.
    [4]DeLeve LD, Shulman HM, McDonald GB.Toxic injury to hepatic sinusoids:sinusoidal obstruction syndrome veno-occlusive disease[J].Semin Liver Dis, 2002, 22 (1) :27-42.
    [5]Mc Donald GB, Hinds MS, Fisher ID, et al.Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation a cohort study of 355 patients[J].Ann Intern Med, 1993, 118 (4) :255-267.
    [6]陈毅鹏, 李君, 柴菊爱, 等.肝静脉闭塞病的临床和病理研究[J].中华消化杂志, 2006, 26 (4) :224-226.
    [7]Jones RJ, Lee KSK, Beschomer WE, et al.Veno-occlusive disease of the liver following bone marrow transplantation[J].Transplantation, 1987, 44 (6) :778-783.
    [8]Mc Donald GB, Sharma P, Matthews DE, et al.Veno-occlusive disease of the liver after bone marrow transplantation:diagnosis, incidence and predisposing factors[J].Hepatology, 1984, 4:116-122.
    [9]Matsumoto Y, Horiike S, Sakagami J, et al.Early ultrasonographic diagnosis and clinical follow-up of hepatic veno-occlusive disease after allogeneic bone marrow transplantation in a patient with acute lymphoblastic leukemia[J].Intern Med, 2009, 48 (10) :831-835.
    [10]Pei YG, Hu DY, Shen YQ, et al.The value of MSCT and MRI in the diagnosis of hepatic veno-occlusive disease[J].Zhonghua Gan Zang Bing Za Zhi, 2010, 18 (2) :150-152.
    [11]Richardson PG, Soiffer RJ, Antin JH.et al.Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation:a multicenter, randomized, dose-finding trial[J].Biol Blood Marrow Transplant, 2010, 16 (7) :1005-1017.
  • 加载中
计量
  • 文章访问数:  4841
  • HTML全文浏览量:  19
  • PDF下载量:  1350
  • 被引次数: 0
出版历程
  • 收稿日期:  2010-11-29
  • 出版日期:  2011-02-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回