胰腺癌的早期诊断

刘旭; 郭晓钟

doi:10.3969/j.issn.1001-5256.2016.05.008

胰腺癌的早期诊断

DOI: 10.3969/j.issn.1001-5256.2016.05.008

刘旭,
郭晓钟

中国人民解放军沈阳军区总医院消化内科

详细信息

中图分类号: R735.9
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出版历程
- 收稿日期: 2016-03-02
- 出版日期: 2016-05-20

Early diagnosis of pancreatic cancer

Department of Gastroenterology,General Hospital of Shenyang Military Area

摘要

摘要: 胰腺癌恶性程度高,预后极差,目前临床早期诊断困难。回顾了胰腺癌发生、发展及转移过程中恶性分子生物学特征的变化及机制,从中分析可能用于胰腺癌临床诊断的靶点。归纳了胰腺癌的临床表现、高危因素、肿瘤标志物、联合检测及新设备在早期诊断中的作用,提出了合理联合应用血清学、影像学检查方法,研究、探寻新的肿瘤标志物均是目前提高临床胰腺癌早期诊断率的重要方法。
- 胰腺肿瘤 /
- 早期诊断 /
- 肿瘤标记,生物学
Abstract: Pancreatic cancer has a high degree of malignancy and a poor prognosis,and at present,early diagnosis of pancreatic cancer is very difficult. This article reviews the changes in molecular biological characteristics in the development,progression,and metastasis of pancreatic cancer and related mechanisms and determines the potential targets for clinical diagnosis of pancreatic cancer. This article also summarizes the clinical manifestations of pancreatic cancer,high- risk factors,tumor markers,and the role of combined determination and new equipment in early diagnosis,and points out that the application of serological and radiological examinations and identification of new tumor markers are important methods to improve the early diagnosis of pancreatic cancer in clinical practice.
- pancreatic neoplasms /
- early diagnosis /
- tumor markers,biological

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参考文献(22)

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