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Primary hepatic neuroendocrine neoplasm: a report of 2 cases and literature review
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摘要:
原发性肝脏神经内分泌肿瘤的国内外报道较为少见,其临床表现及实验室检查缺乏特异性。本文报道了经B超引导下肝穿刺活组织检查并排除其他部位原发性肿瘤而确诊的原发性肝脏神经内分泌肿瘤2例,通过总结其临床表现及影像学检查特点,以提高此病的早期诊断。
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Key words:
- liver neoplasms /
- neuroendocrine tumors /
- case reports
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[1]PARK CH, CHUNG JW, JANG SJ, et al.Clinical features and outcomes of primary hepatic neuroendocrine carcinomas[J].J Gastroenterol Hepatol, 2012, 27 (8) :1306-1311. [2]FENG C, LI Z, HU DY, et al.Computed tomography and magnetic resonance imaging features of pancreatic neuroendocrine tumors[J].Chin J Dig Surg, 2016, 15 (9) :933-939. (in Chinese) 冯翠, 李震, 胡道予, 等.胰腺神经内分泌肿瘤的CT和MRI表现特征[J].中华消化外科杂志, 2016, 15 (9) :933-939. [3] Expert Group of Chinese Consensus on Pathological Diagnosis of Gastroenteropancreatic Neuroendocrine Neoplasm.Chinese consensus on pathological diagnosis of gastroenteropancreatic neuroendocrine neoplasm (2013) [J].Chin J Pathol, 2013, 42 (10) :691-694. (in Chinese) 中国胃肠胰神经内分泌肿瘤病理诊断共识专家组.中国胃肠胰神经内分泌肿瘤病理诊断共识 (2013年版) [J].中华病理学杂志, 2013, 42 (10) :691-694. [4]AKAHORI T, SHO M, TANAKA T, et al.Significant efficacy of newtranscatheter arterial chemoembolization technique for hepatic metastases of pancreatic neuroendocrine tumors[J].Anticancer Res, 2013, 33 (8) :3355-3358. [5]LI XQ, ZHANG H, LI JD.Advances in research of primary hepatic neuroendocrine tumors[J].World Chin J Dig, 2013, 21 (11) :984-989. (in Chinese) 李晓琼, 张华, 李健丁.肝脏原发性神经内分泌肿瘤的研究现状[J].世界华人消化杂志, 2013, 21 (11) :984-989. [6]HUANG YQ, XU F, YANG JM, et al.primary hepatic neuroendocrine carcinoma:clinical analysis of 11 cases[J].Hepatobiliary Pancreat Dis Int, 2010, 9 (1) :44-48. [7]ZHU Z, ZHAO XM, ZHOU CW.Imaging features of primary hepatic endocrine carcinoma[J].Chin J Med Imaging Technol, 2010, 26 (4) :721-723. (in Chinese) 朱正, 赵心明, 周纯武.肝脏原发神经内分泌癌的影像表现[J].中国医学影像技术, 2010, 26 (4) :721-723. [8]RAMAGE JK, AHMED A, ARDILL J, et al.Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs) [J].Gut, 2012, 61:6-32. [9]GURUNG A, YOSHIDA EM, SCUDAMORE CH, et al.Primary hepatic neuroendocrine tumour requiring live donor liver transplantation:case report and concise review[J].Ann Hepatol, 2012, 11 (5) :715-720. [10]FENWICK SW, WYATT JI, TOOGOOD GJ, et al.Hepatic resection and transplantation for primary carcinoid tumors of the liver[J].Ann Surg, 2004, 239 (2) :210-219. [11]LEVY MJ, THOMPSON GB, TOPAZIAN MD, et al.US-guided ethanol ablation of insulinomas:a newtreatment option[J].Gastrointest Endosc, 2012, 75 (1) :200-206. [12]RAYMOND E, DAHAN L, RAOUL JL, et al.Sunitinib malate for the treatment of pancreatic neuroendocrine tumors[J].N Engl J Med, 2011, 364 (6) :501-513. [13]YAO JC, SHAH MH, ITO T, et al.Everolimus for advanced pancreatic neuroendocrine tumors[J].N Engl J Med, 2001, 364 (6) :514-523. -
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