超声造影在肝癌早期诊断及射频消融治疗中的应用价值

陈敏华; 吴薇

doi:10.3969/j.issn.1001-5256.2017.07.002

超声造影在肝癌早期诊断及射频消融治疗中的应用价值

DOI: 10.3969/j.issn.1001-5256.2017.07.002

陈敏华,
吴薇

北京大学肿瘤医院暨北京市肿瘤防治研究所超声科恶性肿瘤发病机制及转化研究教育部重点实验室

详细信息

中图分类号: R445.1;R735.7
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出版历程
- 收稿日期: 2017-05-22
- 出版日期: 2017-07-20

Value of contrast-enhanced ultrasound in early diagnosis of liver cancer and radiofrequency ablation treatment

Chen MinHua,
Wu Wei

Department of Ultrasound, Peking University Cancer Hospital & Institute, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education)

摘要

摘要: 肝细胞癌的早期发现及有效治疗对提高患者生存率至关重要。建立简便有效的早期诊断、普查方法及流程,并进行微创有效的治疗,是提高我国肝癌诊治水平的重要课题。介绍了超声造影在肝癌早期诊断及射频消融规范化治疗中的重要作用。叙述了超声造影对肝硬化背景下的小肝癌及其分化程度的判断,以及增生癌变及癌前病变的鉴别诊断。指出超声造影技术在射频规范化治疗以及治疗方案﹑策略制订方面的重要作用,阐明其可应用于射频治疗前、治疗中及治疗后。
- 肝肿瘤 /
- 超声造影 /
- 导管消融术 /
- 早期诊断 /
- 述评
Abstract: Early identification and effective treatment of hepatocellular carcinoma plays an important role in improving survival rate.The establishment of simple and effective procedures for early diagnosis, census methods, and effective minimally invasive treatment is an important project in China to improve the diagnosis and treatment level of liver cancer.Contrast-enhanced ultrasound plays an important role in the early diagnosis of liver cancer and radiofrequency ablation treatment.This article describes how contrast-enhanced ultrasound helps with the identification of small hepatocellular carcinoma and degree of tumor differentiation in patients with liver cirrhosis, as well as the differential diagnosis of hyperplasia/canceration and precancerous lesion.It also introduces the important role of contrast-enhanced ultrasound in standard radiofrequency ablation and development of therapeutic regimens and strategies and clarifies that it can be used before, during, and after radiofrequency ablation treatment.
- liver neoplasms /
- contrast enhanced ultrasound /
- catheter ablation /
- early diagnosis /
- editorial

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参考文献(18)

[1]DAI Y, CHEN MH, FAN ZH, et al.Diagnosis of small hepatic nodules detected by surveillance ultrasound in patients with cirrhosis:comparison between contrast-enhanced ultrasound and contrast-enhanced helical computed tomography[J].Hepatol Res, 2008, 38 (3) :281-290.

[2]FAN ZH, CHEN MH, DAI Y, et al.Evaluation of primary malignancies of the liver using contrast-enhance sonography:correlation with pathology[J].AJR, 2006, 186 (6) :1512-1519.

[3]CHEN MH, DAI Y, YAN K, et al.The role of contrast-enhanced ultrasound on the diagnosis of small hepatocellular carcinoma (≤3cm) in patients with cirrhosis[J].Hepatol Res, 2006, 35 (4) :281-288.

[4]CHEN MH, YANG W, YAN K, et al.Large liver tumors:protocol for radiofrequency ablation and its clinical application in 110 patientsmathematic model, overlapping mode, and electrode placement process[J].Radiology, 2004, 232 (1) :260-271.

[5]CHEN MH, YANG W, YAN K, et al.The role of contrast-enhanced ultrasound in planning treatment protocols for hepatocellular carcinoma before radiofrequency ablation[J].Clin Radiol, 2007, 62 (8) :752-760.

[6]CHEN MH, YANG W, YAN K, et al.Treatment efficacy of radiofrequency ablation of 338 patients with hepatic malignant tumor and the relevant complications[J].World J Gastroenterol, 2005, 11 (40) :6395-6401.

[7]CHEN MH, DAI Y, YAN K, et al.Primarily diagnostic criteria of focal liver lesions using contrast enhanced ultrasound[J].Chin JUltrasonogr, 2007, 16 (4) :310-313. (in Chinese) 陈敏华, 戴莹, 严昆, 等.肝局灶性病变超声造影诊断指标初探[J].中华超声影像学杂志, 2007, 16 (4) :310-313.

[8] CHEN MH, LIANG P.Chinese guidelines for the application of interventional ultrasound[J].Chin J Med, 2016, 51:59-66. (in Chinese) 陈敏华, 梁萍.中国介入超声应用指南[J].中国医刊, 2016, 51:59-66.

[9]CLAUDON M, DIETRICH CF, CHOI BI, et al.Guidelines and good clinical practice recommendations for Contrast Enhanced Ultrasound (CEUS) in the liver-update 2012:a WFUMB-EFSUMBinitiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS[J].Ultrasound Med Biol, 2013, 39 (2) :188-211.

[10]AHMED M, SOLBIATI L, BRACE CL, et al.Image-guided tumor ablation:standardization of terminology and reporting criteria---a 10-year update[J].Radiology, 2014, 273 (1) :241-260.

[11]CHEN MH, DAI Y, YAN K, et al.Early diagnosis of small hepatocellular carcinoma by new contrast-enhanced ultrasound technique[J].J Peking Univ:Health Sci, 2005, 37 (5) :458-462. (in Chinese) 陈敏华, 戴莹, 严昆, 等.新型超声造影技术对微小肝癌诊断的价值[J].北京大学学报:医学版, 2005, 37 (5) :458-462.

[12]WU W, CHEN M, YAN K, et al.Evaluation of contrast-enhanced ultrasound for diagnosis of dysplastic nodules with a focus of hepatocellular carcinoma in liver cirrhosis patients[J].Chin JCancer Res, 2015, 27 (1) :83-89.

[13]WU W, CHEN MH, YIN SS, et al.The role of CEUS of focal liver lesions before percutaneous biopsy[J].AJR, 2006, 187 (3) :752-761.

[14]CHEN MH, WU W, YANG W, et al.The use of contrast-enhanced ultrasonography in the selection of patients with hepatocellular carcinoma for radio frequency ablation therapy[J].J Ultrasound Med, 2007, 26 (8) :1055-1063.

[15]YANG W, CHEN MH, WANG MQ, et al.Combination therapy of radiofrequency ablation and transarterial chemoembolization in recurrent hepatocellular carcinoma after hepatectomy compared with single treatment[J].Hepatol Res, 2009, 39 (3) :231-240.

[16]ZEGN YR, CHEN MH, YAN K, et al.Identification the invasion range of hepatocellular carcinoma by contrast-enhanced ultrasound[J].Natl Med J China, 2006, 86 (46) :3294-3298. (in Chinese) 曾燕荣, 陈敏华, 严昆, 等.超声造影界定肝癌浸润范围的应用价值[J].中华医学杂志, 2006, 86 (46) :3294-3298.

[17]YAN K, CHEN MH, YANG W, et al.Radiofrequency ablation of hepatocellular carcinoma:long-term outcome and prognostic factors[J].Eur J Radiol, 2008, 67 (2) :336-347.

[18]YANG W, CHEN MH, YIN SS, et al.Radiofrequency ablation of recurrent hepatocellular carcinoma after hepatectomy:therapeutic efficacy on early-and late-phase recurrence[J].AJR, 2006, 186 (5 Suppl) :s275-s283.

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