慢性丙型肝炎抗病毒药物及其治疗方案研究进展

曾群; 揭盛华

doi:10.3969/j.issn.1001-5256.2017.11.033

慢性丙型肝炎抗病毒药物及其治疗方案研究进展

DOI: 10.3969/j.issn.1001-5256.2017.11.033

曾群,
揭盛华

华中科技大学同济医学院附属协和医院感染病科

详细信息

中图分类号: R512.63
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出版历程
- 收稿日期: 2017-05-02
- 出版日期: 2017-11-20

Research advances in antiviral drugs and their treatment regimens in chronic hepatitis C

Department of Infectious Diseases, Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

摘要

摘要: 慢性丙型肝炎成为全球严重的公共卫生问题,近年来随着丙型肝炎的药物治疗不断发展,使丙型肝炎治愈成为可能。从丙型肝炎的流行现状,传统的标准治疗方案（聚乙二醇干扰素+利巴韦林）以及不同的口服小分子直接抗病毒药物（DAAs）的优势及副作用,总结了不同DAAs药物组合对于不同慢性丙型肝炎基因型治疗的利弊,并简要介绍了世界卫生组织对于丙型肝炎治疗的推荐意见。相信未来慢性丙型肝炎的药物治疗会不断飞跃,消灭丙型肝炎指日可待。
- 肝炎,丙型,慢性 /
- 抗病毒药 /
- 治疗 /
- 综述
Abstract: Chronic hepatitis C has become a serious public health issue around the world.In recent years, with the development of pharmacotherapy for hepatitis C, it may be possible to cure hepatitis C.With reference to the epidemic status of hepatitis C and the advantages and side effects of conventional standard therapy (pegylated interferon plus ribavirin) and various oral direct-acting antiviral agents (DAAs) , this article summarizes the advantages and disadvantages of different combinations of DAAs in the treatment of chronic hepatitis C with different genotypes and briefly introduces the World Health Organization recommendations on the treatment of hepatitis C.Hepatitis C is expected to be eliminated with the development of pharmacotherapy for chronic hepatitis C.
- hepatitis C, chronic /
- antiviral agents /
- therapy /
- review

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参考文献(41)

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