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原发性胆汁性胆管炎合并急性甲型肝炎1例报告并文献复习

王乐 王志宇 赵旭 高普均

引用本文:
Citation:

原发性胆汁性胆管炎合并急性甲型肝炎1例报告并文献复习

DOI: 10.3969/j.issn.1001-5256.2018.03.029
详细信息
  • 中图分类号: R575

Primary biliary cholangitis with acute hepatitis A: a case report and literature review

  • 摘要:

    <正>现有研究表明[1],HAV可通过触发自身免疫性机制导致多种自身免疫性疾病,包括自身免疫性肝病。目前,甲型肝炎所致原发性胆汁性胆管炎(PBC)的报道尚少见,现报道1例经病理证实的PBC合并急性甲型肝炎并作相关文献回顾。1病例资料患者男性,58岁,因"乏力、厌食、腹胀、尿黄2周,目黄、面黄7 d"于2016年12月12日收入吉林大学第一医院。病程中诉口干。既往史:否认自身免疫性疾病史及家族史。查体:血

     

  • [1]Tabak F, Ozdemir F, Tabak O, et al.Autoimmune hepatitis induced by the prolonged hepatitis A virus infection[J].Ann Hepatol, 2008, 7 (2) :177-179.
    [2]MIAO Q, MA X.Significance of clinical pathology in diagnosis and treatment of autoimmune liver diseases[J].J Clin Hepatol, 2014, 30 (5) :385-389. (in Chinese) 苗琪, 马雄.临床病理学在自身免疫性肝病诊治中的重要性[J].临床肝胆病杂志, 2014, 30 (5) :385-389.
    [3]HEATHCOTE EJ.Management of primary biliary cirrhosis.The American Association for the Study of Liver Diseases practice guidelines[J].Hepatology, 2000, 31 (4) :1005-1013.
    [4]Chinese Society of Hepatology, Chinese Medical Association;Chinese Society of Gastroenterology, Chinese Medical Association;Chinese Society of Infectious Disease, Chinese Medical Association.Consensus on the diagnosis and management of primary biliary cirrhosis (cholangitis) (2015) [J].J Clin Hepatol, 2015, 31 (12) :1980-1988. (in Chinese) 中华医学会肝病学分会, 中华医学会消化病学分会, 中华医学会感染病学分会.原发性胆汁性肝硬化 (又名原发性胆汁性胆管炎) 诊断和治疗共识 (2015) [J].临床肝胆病杂志, 2015, 31 (12) :1980-1988.
    [5]BI JB, LI ZY, GU JX, et al.Clinical characteristics of primary biliary cirrhosis:a retrospective analysis of 101 cases[J/CD].Chin J Hepatic Surg:Electronic Edition, 2017, 4 (6) :316-319. (in Chinese) 毕建斌, 李泽宇, 顾静娴, 等.101例原发性胆汁性肝硬化患者的临床特征回顾性分析[J/CD].中华肝脏外科手术学电子杂志, 2017, 4 (6) :316-319.
    [6]ZHAO N, LI ZW.An analysis of clinical features of hepatitis A in adults[J].Chin J Pract Intern Med, 2007, 27 (19) :1537-1538. (in Chinese) 赵宁, 李智伟.成人甲型病毒性肝炎临床特点分析[J].中国实用内科杂志, 2007, 27 (19) :1537-1538.
    [7]LIN XM, PAN QS, ZHANG WH, et al.Autoimmunity of patients after chronic hepatitis B infection[J].Chin J Nosocomiol, 2009, 19 (8) :889-891. (in Chinese) 林晓梅, 潘钦石, 张文辉, 等.慢性乙型肝炎患者产生自身免疫的研究[J].中华医院感染学杂志, 2009, 19 (8) :889-891.
    [8]FAN Q, BAO J, YAO D, et al.Study on the detection and clinical significance of serum autoantibodies in patients with hepatitis C virus infection[J].Modern Prevent Med, 2014, 41 (2) :311-313, 316. (in Chinese) 范琪, 包金, 姚迪, 等.丙型肝炎病毒感染者血清自身抗体检测及临床意义研究[J].现代预防医学, 2014, 41 (2) :311-313, 316.
    [9]WANG MC, XU AF, LIU Y.Clinical significance of autoantibody detection in progression of chronic hepatitis B[J].Chin J Health Lab Technol, 2015, 25 (6) :852-853, 859. (in Chinese) 王妙婵, 徐爱芳, 刘苑.慢性乙肝进展过程中自身抗体检测的临床意义[J].中国卫生检验杂志, 2015, 25 (6) :852-853, 859.
    [10]ZHANG Y, WANG HX, LYU Y.Clinical analysis of the detection of auto-antibody in patients with chronic hepatitis C[J].Med J Natl Defending Forces Southwest China, 2004, 14 (2) :166-167. (in Chinese) 张悦, 王惠萱, 吕耀.慢性丙型肝炎患者自身抗体检测的临床分析[J].西南国防医药, 2004, 14 (2) :166-167.
    [11]HE XM, LI SW, LYU TX, et al.Study on the diagnostic significance of level of serum autoantibodies in fibrosis staging in patients with chronic HBV hepatitis[J].Clin Exp Med, 2016, 7 (15) :632-636. (in Chinese) 何肖敏, 李斯文, 吕婷霞, 等.血清自身抗体在乙肝肝纤维化分期中的诊断价值研究[J].临床和实验医学杂志, 2016, 7 (15) :632-636.
    [12]KAMMER AR, van der BURG SH, GRABSCHEID B, et al.Molecular mimicry of human cytochrome P450 by hepatitis C virus at the level of cytotoxic T cell recognition[J].J Exp Med, 1999, 190 (2) :169-176.
    [13]MANANGEESWARAN M, JACQUES J, TAMI C, et al.Binding of hepatitis A virus to its cellular receptor 1 inhibits T-regulatory cell functions in humans[J].Gastroenterology, 2012, 142 (7) :1516-1525.
    [14]KIM YD, KIM KA, ROU WS, et al.A case of autoimmune hepatitis following acute hepatitis A[J].Korean J Gastroenterol, 2011, 57 (5) :315-318.
    [15]HEURGUEA, BERNARD-CHABERT B, PICOT R, et al.Overlap syndrome triggered by acute viral hepatitis A[J].Eur J Gastroenterol Hepatol, 2009, 21 (6) :708-709.
    [16]VENTO S, GAROFANO T, DI PG, et al.Identification of hepatitis A virus as a trigger for autoimmune chronic hepatitis type 1 in susceptible individuals[J].Lancet, 1991, 337 (8751) :1183-1187.
    [17]FAN XQ, WANG CS, LIU JT, et al.Clinical treatment progress of ursodeoxycholic acid in primary biliary cirrhosis[J].China Med Herald, 2016, 13 (24) :58-61. (in Chinese) 樊雪强, 王彩生, 刘金涛, 等.熊去氧胆酸在原发性胆汁性肝硬化临床治疗中的进展[J].中国医药导报, 2016, 13 (24) :58-61.
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