细胞外囊泡与肝脏疾病发生发展的关系

王江瑜; 王志鑫; 樊海宁

doi:10.3969/j.issn.1001-5256.2018.03.048

细胞外囊泡与肝脏疾病发生发展的关系

DOI: 10.3969/j.issn.1001-5256.2018.03.048

1. 青海大学
2. 青海大学附属医院肝胆胰外科
3. 青海省包虫病重点实验室

基金项目:

青海省人畜包虫病防控策略与创新技术应用(2016-SF-A5)；

详细信息

中图分类号: R575
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出版历程
- 出版日期: 2018-03-20

Role of extracellular vesicles in the development and progression of liver diseases

Qinghai University

Research funding:

摘要

摘要: 细胞外囊泡(EV)是细胞释放到细胞外环境中的膜结合小泡,能够选择性地富集特定蛋白和RNA,介导细胞间通讯。因此,EV具有作为疾病的生物标志物、治疗靶标和传递载体的潜力。总结了EV在病毒性肝炎、肝纤维化和肝癌中的研究进展,探讨其在肝脏疾病中所发挥的作用,以强调EV在未来肝脏疾病研究中的应用前景。
- 细胞外囊泡 /
- 肝炎,病毒性,人 /
- 肝硬化 /
- 肝肿瘤 /
- 综述
Abstract: Extracellular vesicles ( EVs) are membrane-bound vesicles released by cells into the extracellular environment and can selectively enrich specific proteins and RNA and mediate intercellular communication. Therefore, EVs have the potential of a biomarker for diseases, a therapeutic target, and a delivery vector. This article reviews the research advances in the role of EVs in viral hepatitis, liver fibrosis, and liver cancer and emphasizes the prospects of EVs in liver diseases.
- extracellular vesicles /
- hepatitis, viral, human /
- liver cirrhosis /
- liver cancers /
- liver neoplasms

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参考文献(45)

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