中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

影像学诊断技术在非酒精性脂肪性肝病中的应用价值

洪佳 施漪雯 吴晓宁 尤红

引用本文:
Citation:

影像学诊断技术在非酒精性脂肪性肝病中的应用价值

DOI: 10.3969/j.issn.1001-5256.2018.12.041
详细信息
  • 中图分类号: R575.5;R445

Application value of imaging diagnosis in nonalcoholic fatty liver disease

  • 摘要: 非酒精性脂肪性肝病的病程进展漫长,病变复杂多样,临床分期较为困难。肝穿刺病理是诊断脂肪肝的金标准,但在临床应用过程中受到诸多限制,因此如何通过无创手段准确检测脂肪肝是目前研究热点。影像学检查可定性、定量评估肝脂肪变性及纤维化,具有较好的应用前景。重点介绍了近年来非酒精性脂肪性肝病无创诊断在影像学方面的相关进展。

     

  • [1] BOHTE A, van WERVEN J, BIPAT S, et al. The diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis compared with liver biopsy:A meta-analysis[J]. Eur Radiol, 2011, 21 (1) :87-97.
    [2] BEDOSSA P, PATEL K. Biopsy and noninvasive methods to assess progression of nonalcoholic fatty liver disease[J]. Gastroenterology, 2016, 150 (8) :1811-1822.
    [3] CASTERA L, VILGRAIN V, ANGULO P. Noninvasive evaluation of NAFLD[J]. Nat Rev Gastroenterol Hepatol, 2013, 10 (11) :666-675.
    [4] ZHUANG XF, SUN J, WANG XB, et al. Performance of transient elastography in diagnosis of nonalcoholic fatty liver disease[J]. J Clin Hepatol, 2017, 33 (12) :2366-2371. (in Chinese) 庄小芳, 孙洁, 王晓波, 等.瞬时弹性成像技术诊断非酒精性脂肪性肝病的性能评估[J].临床肝胆病杂志, 2017, 33 (12) :2366-2371.
    [5] BERZIGOTTI A. Getting closer to a point-of-care diagnostic assessment in patients with chronic liver disease:controlled attenuation parameter for steatosis[J]. J Hepatol, 2014, 60 (5) :910-912.
    [6] KARLAS T, PETROFF D, SASSO M, et al. Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis[J]. J Hepatol, 2017, 66 (5) :1022-1030.
    [7] CHAN WK, NIK MUSTAPHA NR, MAHADEVA S, et al. Can the same controlled attenuation parameter cut-offs be used for M and XL probes for diagnosing hepatic steatosis?[J]. J Gastroenterol Hepatol, 2018.[Epub ahead of print]
    [8] WONG VW, CHU WC, WONG GL, et al. Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese:a population study using proton-magnetic resonance spectroscopy and transient elastography[J]. Gut, 2012, 61 (3) :409-415.
    [9] BANERJEE R, PAVLIDES M, TUNNICLIFFE E, et al. Multiparametric magnetic resonance for the non-invasive diagnosis of liver disease[J]. J Hepatol, 2014, 60 (1) :69-77.
    [10] OOI G, EARNEST A, KEMP W, et al. Evaluating feasibility and accuracy of non-invasive tests for nonalcoholic fatty liver disease in severe and morbid obesity[J]. Int J Obes (Lond) , 2018.[Epub ahead of print]
    [11] WONG V, WONG G, YEUNG D, et al. Incidence of non-alcoholic fatty liver disease in Hong Kong:A population study with paired proton-magnetic resonance spectroscopy[J]. J Hepatol, 2015, 62 (1) :182-189.
    [12] KRAMER H, PICKHARDT P, KLIEWER M, et al. Accuracy of liver fat quantification with advanced CT, MRI, and ultrasound techniques:Prospective comparison with MR spectroscopy[J]. AJR Am J Roentgenol, 2017, 208 (1) :92-100.
    [13] PARK C, NGUYEN P, HERNANDEZ C, et al. Magnetic resonance elastography vs transient elastography in detection of fibrosis and noninvasive measurement of steatosis in patients with biopsyproven nonalcoholic fatty liver disease[J]. Gastroenterology, 2017, 152 (3) :598-607. e592.
    [14] MEISAMY S, HINES CD, HAMILTON G, et al. Quantification of hepatic steatosis with T1-independent, T2-corrected MR imaging with spectral modeling of fat:Blinded comparison with MR spectroscopy[J]. Radiology, 2011, 258 (3) :767-775.
    [15] NEGRETE L, MIDDLETON M, CLARK L, et al. Inter-examination precision of magnitude-based MRI for estimation of segmental hepatic proton density fat fraction in obese subjects[J]. J Magn Reson Imaging, 2014, 39 (5) :1265-1271.
    [16] NOUREDDIN M, LAM J, PETERSON MR, et al. Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials[J]. Hepatology, 2013, 58 (6) :1930-1940.
    [17] AJMERA V, PARK CC, CAUSSY C, et al. Magnetic resonance imaging proton density fat fraction associates with progression of fibrosis in patients with nonalcoholic fatty liver disease[J]. Gastroenterology, 2018.[Epub ahead of print]
    [18] CASSINOTTO C, BOURSIER J, DE L DINGHEN V, et al. Liver stiffness in nonalcoholic fatty liver disease:A comparison of supersonic shear imaging, FibroScan, and ARFI with liver biopsy[J].Hepatology, 2016, 63 (6) :1817-1827.
    [19] HASHEMI S, ALAVIAN S, GHOLAMI-FESHARAKI M. Assessment of transient elastography (FibroScan) for diagnosis of fibrosis in non-alcoholic fatty liver disease:A systematic review and meta-analysis[J]. Caspian J Intern Med, 2016, 7 (4) :242-252.
    [20] National Workshop on Fatty Liver and Alcoholic Liver Disease, Chinese Society of Hepatology, Chinese Medical Association; Fatty Liver Expert Committee, Chinese Medical Doctor Association. Guidelines of prevention and treatment for nonalcoholic fatty liver disease:A 2018 update[J]. J Clin Hepatol, 2018, 34 (5) :947-957. (in Chinese) 中华医学会肝病学分会脂肪肝和酒精性肝病学组, 中国医师协会脂肪性肝病专家委员会.非酒精性脂肪性肝病防治指南 (2018年更新版) [J].临床肝胆病杂志, 2018, 34 (5) :947-957.
    [21] BOURSIER J, VERGNIOL J, GUILLET A, et al. Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by Fibro Scan in non-alcoholic fatty liver disease[J]. J Hepatol, 2016, 65 (3) :570-578.
    [22] KAMARAJAH SK, CHAN WK, NIK MUSTAPHA NR, et al. Repeated liver stiffness measurement compared with paired liver biopsy in patients with non-alcoholic fatty liver disease[J]. Hepatol Int, 2018, 12 (1) :44-55.
    [23] NOBILI V, VIZZUTTI F, ARENA U, et al. Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis[J]. Hepatology, 2008, 48 (2) :442-448.
    [24] HANNAH W, HARRISON S. Noninvasive imaging methods to determine severity of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis[J]. Hepatology, 2016, 64 (6) :2234-2243.
    [25] PETTA S, WONG V, CAMM C, et al. Improved noninvasive prediction of liver fibrosis by liver stiffness measurement in patients with nonalcoholic fatty liver disease accounting for controlled attenuation parameter values[J]. Hepatology, 2017, 65 (4) :1145-1155.
    [26] IMAJO K, KESSOKU T, HONDA Y, et al. Magnetic resonance imaging more accurately classifies steatosis and fibrosis in patients with nonalcoholic fatty liver disease than transient elastography[J]. Gastroenterology, 2016, 150 (3) :626-637. e627.
    [27] CUI J, HEBA E, HERNANDEZ C, et al. Magnetic resonance elastography is superior to acoustic radiation force impulse for the diagnosis of fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease:A prospective study[J]. Hepatology, 2016, 63 (2) :453-461.
    [28] CAUSSY C, CHEN J, ALQUIRAISH MH, et al. Association between obesity and discordance in fibrosis stage determination by magnetic resonance vs transient elastography in patients with nonalcoholic liver disease[J]. Clin Gastroenterol Hepatol, 2018.[Epub ahead of print]
    [29] HAYASHI T, SAITOH S, FUKUZAWA K, et al. Noninvasive assessment of advanced fibrosis based on hepatic volume in patients with nonalcoholic fatty liver disease[J]. Gut Liver, 2017, 11 (5) :674-683.
    [30] AJMERA V, LOOMBA R. Can Elastography differentiate isolated fatty liver from nonalcoholic steatohepatitis?[J]. Semin Liver Dis, 2018, 38 (1) :14-20.
    [31] LOOMBA R, CUI J, WOLFSON T, et al. Novel 3D magnetic resonance elastography for the noninvasive diagnosis of advanced fibrosis in NAFLD:A prospective study[J]. Am J Gastroenterol, 2016, 111 (7) :986-994.
    [32] LEE MS, BAE JM, JOO SK, et al. Prospective comparison among transient elastography, supersonic shear imaging, and ARFI imaging for predicting fibrosis in nonalcoholic fatty liver disease[J]. PLo S One, 2017, 12 (11) :e0188321.
    [33] XIAO G, ZHU S, XIAO X, et al. Comparison of laboratory tests, ultrasound, or magnetic resonance elastography to detect fibrosis in patients with nonalcoholic fatty liver disease:A meta-analysis[J]. Hepatology, 2017, 66 (5) :1486-1501.
  • 加载中
计量
  • 文章访问数:  1587
  • HTML全文浏览量:  9
  • PDF下载量:  378
  • 被引次数: 0
出版历程
  • 出版日期:  2018-12-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回