囊型包虫病药物新剂型研发及新药开发现状

尹杰; 樊海宁; 温浩; 王海久; 张灵强; 庞明泉; 顾贤波; 王涛; 潘思宇

doi:10.3969/j.issn.1001-5256.2019.04.045

囊型包虫病药物新剂型研发及新药开发现状

DOI: 10.3969/j.issn.1001-5256.2019.04.045

1. 青海大学研究生院
2. 青海大学附属医院肝胆胰外科
3. 青海省包虫病研究重点实验室
4. 新疆医科大学第一附属医院

基金项目:

2017国家重点研发计划“精准医学研究”专项(2017YFC0909900)；青海省包虫病临床医学研究中心项目(2017-SF-L2)； 2016青海省卫生计生委重点课题(2016-wjtg-04)；

详细信息

中图分类号: R532.32
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出版历程
- 出版日期: 2019-04-20

Current status of the research and development of new formulations and drugs for cystic echinococcosis

Graduate School of Qinghai University

Research funding:

摘要

摘要: 囊型包虫病(CE)由细粒棘球蚴感染引起,可累及全身器官。手术是治疗CE的主要方法。随着技术发展、精准手术及无瘤手术标准的引用,CE的手术禁区越来越小,但仍有许多患者因为无法手术而只能选择药物保守治疗。然而,目前治疗CE的药物选择很少,仅有苯并咪唑一类有较确切的疗效。现回顾目前国内外CE的药物治疗研究进展,为药物开发研究及临床药物应用选择提供参考。
- 棘球蚴病,肝 /
- 药用制剂 /
- 综述
Abstract: Cystic echinococcosis ( CE) is a zoonotic parasitic disease caused by Echinococcus granulosus infection and can involve the organs in the whole body. Surgery is the primary method for the treatment of CE. With the development of related techniques, precision operation, and no-tumor operation standards, more and more patients are able to receive surgical treatment, but there are still many patients who can only receive drug conservative treatment. However, there are limited drugs for the treatment of CE at present, and only benzimidazole has a definite therapeutic effect. This article reviews the research advances in the pharmacotherapy for CE in China and foreign countries, so as to provide a reference for drug research and development and clinical drug use.
- echinococcosis, hepatic /
- pharmaceutical preparations /
- review

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参考文献(43)

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