新型冠状病毒肺炎合并肝脏损伤的预防及诊疗方案

中国医师协会消化医师分会, 中华医学会肝病学分会

doi:10.3969/j.issn.1001-5256.2020.04.008

新型冠状病毒肺炎合并肝脏损伤的预防及诊疗方案

DOI: 10.3969/j.issn.1001-5256.2020.04.008

中国医师协会消化医师分会, 中华医学会肝病学分会

详细信息

中图分类号: R575;R563.1
计量
- 文章访问数: 1613
- HTML全文浏览量: 32
- PDF下载量: 362
- 被引次数: 0
出版历程
- 出版日期: 2020-04-20

The protocol for prevention,diagnosis and treatment of liver injury in coronavirus disease 2019

China Digestion Association, Chinese Medical Doctor Association; Chinese Society of Hepatology, Chinese Medical Association

摘要

摘要:
<正>新型冠状病毒肺炎（世界卫生组织命名为2019-冠状病毒病,coronavirus disease 2019,COVID-19）是一种新发的主要经呼吸道传播的急性病毒性疾病,其主要特点是传播快、人群普遍易感,临床主要表现为发热、干咳和乏力,少部分患者有全身肌肉酸痛,重症患者多在发病1周后出现急性呼吸困难和（或）低氧血症,其病死率为1%～3%[1-3]。临床实践和有关文献报道显示,部分患者可有不同程度的肝脏生化学异常。为帮助临床医生积极预防、及时诊断和有效治疗本病相关肝损伤,受中国医师协会消化医师分会和中华医学会肝病学分会委托,邀请
- 诊断 /
- 治疗 /
- 预防 /
- 肝损伤 /
- 新型冠状病毒肺炎
- diagnosis /
- therapy /
- prevention /
- liver injury /
- coronavirus disease 2019

HTML全文

参考文献(20)

[1] GUAN WJ,NI ZY,HU Y,et al. Clinical characteristics of coronavirus disease 2019 in China[J]. N Engl J Med,2020.[Epub ahead of print]

[2] World Health Organization. Novel coronavirus(2019-n Co V)situation report–22[EB/OL]. https://www. who. int/docs/default-source/coronaviruse/situation-reports/20200211-sitrep-22-ncov. pdf? sfvrsn=fb6d49b1_2

[3] Notice on the temporary naming of novel coronavirus pneumonia by the National Health Commission of the People’s Republic of China[EB/OL]. http://www. nhc. gov. cn/mohwsbwstjxxzx/s2908/202002/f15dda000f6a46b2a1ea1377cd80434d. shtml.(in Chinese)国家卫生健康委关于新型冠状病毒肺炎暂命名事宜的通知[EB/OL]. http://www. nhc. gov. cn/mohwsbwstjxxzx/s2908/202002/f15dda000f6a46b2a1ea1377cd80434d. shtml.

[4] XU Z,SHI L,WANG Y,et al. Pathological findings of COVID-19associated with acute respiratory distress syndrome[J]. Lancet Respir Med,2020.[Epub ahead of print]

[5] GUAN GW,GAO L,WANG JW,et al. Exploring the mechanism of liver enzyme abnormalities in patients with novel coronavirus-infected pneumonia[J]. Chin J Heaptol,2020,28(2):100-106.(in Chinese)关贵文，高林，王建文，等．新型冠状病毒感染肺炎患者肝酶异常的机制探究[J]．中华肝脏病杂志，2020,28(2):100-106.

[6] HUANG C,WANG Y,LI X,et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan,China[J].Lancet,2020,395(10223):497-506.

[7] HU LW,WANG WJ,ZHU QJ,et al. Novel coronavirus pneumonia-related liver injury:Etiological analysis and treatment strategy[J]. Chin J Heaptol,2020,28(2):97-99.(in Chinese)胡利琳，王炜珺，朱清静，等．新型冠状病毒感染肺炎相关肝损伤:病因分析及治疗策略[J]．中华肝脏病杂志，2020,28(2):97-99.

[8] LING Y,XU SB,LIN YX,et al. Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients[J]. Chin Med J,2020.[Epub ahead of print]

[9] WASEEM N,CHEN PH. Hypoxic hepatitis:A review and clinical update[J]. J Clin Transl Hepatol,2016,4(3):263-268.

[10] QIAN ZP,MEI X,ZHANG YY,et al. Analysis of baseline liver biochemical parameters in 324 cases with novel coronavirus pneumonia in Shanghai area[J]. Chin J Hepatol,2020,28(3):229-233.(in Chinese)钱志平，梅雪，张宇一，等．上海地区324例新型冠状病毒肺炎患者基线肝功能分析[J]．中华肝脏病杂志，2020,28(3):229-233.

[11] CHEN N,ZHOU M,DONG X,et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan,China:A descriptive study[J]. Lancet,2020,395(10223):507-513.

[12] WANG SH,HAN P,XIAO F,et al. Manifestations of liver injury in 333 hospitalized patients with coronavirus disease 2019[J].Chin J Dig,2020,40(2020-03-09).(in Chinese)汪姝惠，韩平，肖芳，等．新型冠状病毒肺炎住院患者333例的肝损伤表现[J]．中华消化杂志，2020,40(2020-03-09).

[13] YAO N,WANG SN,LIAN JQ,et al. Clinical characteristics and influencing factors of patients with novel coronavirus pneumonia combined with liver injury in Shaanxi region[J]. Chin J Heaptol,2020,28(3):234-239.(in Chinese)姚娜，王素娜，连建奇，等．陕西地区新型冠状病毒肺炎合并肝损伤患者的临床特征与影响因素[J]．中华肝脏病杂志，2020,28(3):234-239.

[14] ZHANG C,SHI L,WANG FS. Liver injury in COVID-19:Management and challenges[J]. Lancet Gastroenterol Hepatol,2020.[Epub ahead of print]

[15] XU XW,WU XX,JIANG XG,et al. Clinical findings in a group of patient infected with the 2019 novel coronavirus(SARSCov-2)outside of Wuhan,China:Retrospective case series[J]. BMJ,2020.[Epub ahead of print]

[16] SHI H,HAN X,JIANG N,et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan,China:A descriptive study[J]. Lancet Infect Dis,2020.[Epub ahead of print]

[17] WANG D,HU B,HU C,et al. Clinical characteristics of 138hospitalised patients with 2019 novel coronavirus-infected pneumonia in Wuhan,China[J]. JAMA,2020.[Epub ahead of print]

[18] LIU C,JIANG ZC,SHAO CX,et al. Preliminary study of the relationship between novel coronavirus pneumonia and liver function damage:A multicenter study[J]. Chin J Heaptol,2020,28(2):107-111.(in Chinese)刘川，江自成，邵初晓，等．新型冠状病毒肺炎与肝功能损伤的关系初探:一项多中心研究[J]．中华肝脏病杂志，2020,28(2):107-111.

[19] Liver Failure and Artificial Liver Group,Chinese Society of Infectious Diseases,Chinese Medical Association; Severe Liver Disease and Artificial Liver Group,Chinese Society of Hepatology,Chinese Medical Association. Guideline for diagnosis and treatment of liver failure(2018)[J]. J Clin Hepatol,2019,35(1):38-44.(in Chinese)中华医学会感染病学分会肝衰竭与人工肝学组，中华医学会肝病学分会重型肝病与人工肝学组．肝衰竭诊治指南(2018年版)[J]．临床肝胆病杂志，2019,35(1):38-44.

[20] Drug-induced Liver Disease Study Group,Chinese Society of Hepatology,Chinese Medical Association. Guidelines for the management of drug-induced liver injury[J]. J Clin Hepatol,2015,31(11):1752-1769.(in Chinese)中华医学会肝病学分会药物性肝病学组．药物性肝损伤诊治指南[J]．临床肝胆病杂志，2015,31(11):1752-1769.

施引文献

资源附件(0)

访问统计