肠道微生态与肝性脑病的关系

黄云义; 刘尧; 张群; 时克; 王宪波

doi:10.3969/j.issn.1001-5256.2020.04.045

肠道微生态与肝性脑病的关系

DOI: 10.3969/j.issn.1001-5256.2020.04.045

首都医科大学附属北京地坛医院中西医结合中心

基金项目:

首都卫生发展科研专项(首发2018-1-2172)；北京市医院管理局临床医学发展专项经费资助(ZYLX201707)；北京市科学技术委员会资助(Z191100006619033)；

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中图分类号: R575.3
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出版历程
- 出版日期: 2020-04-20

Association of intestinal microecology with hepatic encephalopathy

Department of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University

Research funding:

摘要

摘要: 肝性脑病(HE)是肝硬化患者常见的一种复杂的神经精神性并发症,具有高发病率、高复发率及高病死率的特点,也是住院和再住院风险增加的一个重要因素。目前对于HE的治疗尚无特效药物,近年来研究发现,肠道微生态变化与HE的发生、发展及预后相关,而且调整肠道菌群对HE有一定的预防性作用。旨在对近年来肠道微生态与HE之间关系的研究进行总结,希望为临床防治HE提供新的治疗思路。
- 胃肠道微生物组 /
- 肝性脑病 /
- 肝硬化
Abstract: Hepatic encephalopathy( HE) is a common and complex neuropsychiatric complication in patients with liver cirrhosis and has the features of high incidence,recurrence,and mortality rates,and it is also an important factor for the increased risk of hospitalization and rehospitalization. At present,there are still no effective drugs for HE. Recent studies have found that intestinal microecological changes are associated with the development,progression,and prognosis of HE,and the regulation of intestinal flora has a certain preventive effect on HE.This article summarizes the research on the association between intestinal microecology and HE in recent years and hopes to provide new ideas for clinical prevention and treatment of HE.
- gastrointestinal microbiome /
- hepatic encephalopathy /
- liver cirrhosis

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参考文献(37)

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