原发性胆汁性胆管炎合并肝外自身免疫性疾病的研究进展

涂荣芳; 杨雪; 唐映梅

doi:10.3969/j.issn.1001-5256.2020.06.046

原发性胆汁性胆管炎合并肝外自身免疫性疾病的研究进展

DOI: 10.3969/j.issn.1001-5256.2020.06.046

昆明医科大学第二附属医院消化内科

基金项目:

国家自然科学基金(81660102)；云南省高层次人才培养项目(D-201629)；

详细信息

中图分类号: R575.7;R593.2
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出版历程
- 出版日期: 2020-06-20

Research advances in primary biliary cholangitis with extrahepatic autoimmune diseases

Research funding:

摘要

摘要:
原发性胆汁性胆管炎(PBC)是一种慢性自身免疫性肝病,以肝内小胆管进行性破坏为主要特征。PBC患者常合并肝外自身免疫性疾病,可累及胃肠道、肺、风湿免疫系统、内分泌系统等多个器官及系统。对PBC合并肝外自身免疫性疾病的疾病谱、发病机制、治疗及预后研究进展进行总结。
- 原发性胆汁性胆管炎 /
- 自身免疫疾病 /
- 病理过程 /
- 治疗学 /
- 预后
Abstract:
Primary biliary cholangitis( PBC) is a chronic autoimmune liver disease characterized by progressive destruction of the small intrahepatic bile ducts. Patients with PBC often have extrahepatic autoimmune diseases,which can involve multiple organs and systems including the gastrointestinal tract,lung,rheumatoid immune system,and endocrine system. This article summarizes the research advances in the disease spectrum,pathogenesis,treatment,and prognosis of PBC with extrahepatic autoimmune disease.
- primary biliary cholangitis /
- autoimmune diseases /
- pathologic processes /
- therapeutics /
- prognosis

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参考文献(43)

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