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原发性胆汁性胆管炎患者中枢神经系统改变相关研究进展

胡一男 尚玉龙 周新民

引用本文:
Citation:

原发性胆汁性胆管炎患者中枢神经系统改变相关研究进展

DOI: 10.3969/j.issn.1001-5256.2021.10.003
详细信息
    通信作者:

    周新民,zhouxmm@fmmu.edu.cn

  • 中图分类号: R575.22

Research advances in central nervous system changes in patients with primary biliary cholangitis

  • 摘要: 原发性胆汁性胆管炎(PBC)是一种以胆汁淤积为主要表现的自身免疫性肝病,好发于中老年女性。大约50%的患者伴有乏力和瘙痒,20%的患者伴有抑郁或者情绪的改变。近年有研究证明,PBC患者非特异性症状如乏力、瘙痒以及认知改变等症状与中枢神经系统结构和功能改变存在联系。通过大脑影像学改变及早期发现临床前期的PBC患者,可能成为该病早期诊断的检查手段。

     

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  • 收稿日期:  2021-08-11
  • 录用日期:  2021-09-04
  • 出版日期:  2021-10-20
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