肝硬化患者营养不良和衰弱的评估与临床管理

张一骏; 张茜; 罗新华

doi:10.3969/j.issn.1001-5256.2022.07.035

肝硬化患者营养不良和衰弱的评估与临床管理

DOI: 10.3969/j.issn.1001-5256.2022.07.035

张一骏¹,
张茜²,
罗新华^3, , ,

1.
贵州医科大学附属医院感染科，贵阳 550000
2.
贵州省人民医院感染科，贵阳 550000
3.
贵州医科大学附属人民医院感染科，贵阳 550000

基金项目:

贵州省科学技术基金重点项目 (Qiankehe Basis-ZK[2021] Priority013)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：张一骏负责撰写文章; 张茜参与修改文章内容; 罗新华参与文章的最终定稿。

详细信息

通信作者:
罗新华，luoxh09@163.com

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- 被引次数: 0
出版历程
- 收稿日期: 2021-11-18
- 录用日期: 2021-12-26
- 出版日期: 2022-07-20

Assessment and clinical management of malnutrition and asthenia in patients with liver cirrhosis

1.
Department of Infectious Diseases, The Affiliated Hospital of Guizhou Medical University, Guiyang 550000, China
2.
Department of Infectious Diseases, Guizhou Provincial People's Hospital, Guiyang 550000, China
3.
Department of Infectious Diseases, The Affiliated People's Hospital of Guizhou Medical University, Guiyang 550000, China

Research funding:

Major Project of Science and Technology Fund of Guizhou Province (Qiankehe Basis-ZK[2021] Priority013)

More Information

Corresponding author: LUO Xinhua, luoxh09@163.com (ORCID: 0000-0002-0323-3868)

摘要

摘要: 肝硬化患者营养不良和衰弱是相互联系的多维度问题。营养不良是导致机体衰弱的原因之一，而衰弱是人体机能障碍的综合表现，二者相互作用并进一步影响肝硬化患者的临床转归。因此，应及早发现、准确评估并积极治疗营养不良和衰弱，以减少临床并发症、延长生存期及改善生活质量。在针对肝硬化病因及并发症治疗的基础上，加强营养管理和体育锻炼是治疗营养不良及机体衰弱的主要措施，而睾酮替代等药物治疗的临床效果尚需进一步研究。
- 肝硬化 /
- 营养不良 /
- 衰弱 /
- 临床管理
Abstract: Malnutrition and asthenia are interrelated and multidimensional problems in patients with liver cirrhosis. Malnutrition is one of the reasons leading to asthenia, whereas asthenia is a comprehensive manifestation of functional disorders, and malnutrition and asthenia interact with each other and further affect the clinical outcome of patients with liver cirrhosis. Therefore, early identification, accurate assessment, and active treatment of malnutrition and asthenia should be taken seriously to reduce clinical complications, prolong survival time, and improve quality of life. In addition to the therapies targeting the etiology and complications of liver cirrhosis, nutritional management and physical exercise are the main measures for the treatment of malnutrition and asthenia, and further studies are needed to explore the clinical efficacy of medical treatment such as testosterone replacement therapy.
- Liver Cirrhosis /
- Malnutrition /
- Frailty /
- Clinical Governance

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参考文献(38)

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