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竞争性内源RNA在胆管细胞癌发生发展中的作用

徐宝麟 成雨 魏勇

引用本文:
Citation:

竞争性内源RNA在胆管细胞癌发生发展中的作用

DOI: 10.3969/j.issn.1001-5256.2022.11.044
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:徐宝麟负责资料收集与分析,撰写论文;魏勇、成雨负责拟定写作思路,指导撰写文章并最后定稿。
详细信息
    通信作者:

    魏勇,weiyonglancet@163.com

The role of competitive endogenous RNA in the development of cholangiocarcinoma

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  • 摘要: 竞争性内源RNA是能够竞争性结合miRNA的一类转录产物,主要包括长链非编码RNA及环状RNA等,参与多种肿瘤的发生过程。胆管癌恶性程度高,预后差,治疗手段有限,发病机制复杂。竞争性内源RNA,特别是长链非编码RNA和环状RNA,能够通过影响胆管癌细胞的生物学行为、细胞代谢、炎症过程、上皮-间质转化过程影响胆管癌的发生发展。本文对长链非编码RNA与环状RNA在胆管细胞癌发生中的作用进行综述,以期进一步阐明胆管癌的发病机制。

     

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  • 收稿日期:  2022-03-13
  • 录用日期:  2022-05-15
  • 出版日期:  2022-11-20
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