扩大慢性乙型肝炎治疗

庄辉

doi:10.3969/j.issn.1001-5256.2023.01.001

扩大慢性乙型肝炎治疗

DOI: 10.3969/j.issn.1001-5256.2023.01.001

庄辉^,

北京大学基础医学院病原生物学系暨感染病研究中心，北京 100191

利益冲突声明：作者声明不存在利益冲突。

详细信息

通信作者:
庄辉，zhuangbmu@126.com

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出版历程
- 收稿日期: 2022-11-18
- 出版日期: 2023-01-20

Expanding the treatment of chronic hepatitis B

Hui ZHUANG^,

Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University, Beijing 100191, China

More Information

Corresponding author: ZHUANG Hui, zhuangbmu@126.com

摘要

摘要:
全球符合治疗标准的慢性乙型肝炎患者中，仅5%接受抗病毒治疗。现行指南治疗标准过严是慢性乙型肝炎患者治疗率低的原因之一。扩大现行指南确定的慢性乙型肝炎治疗标准将减轻疾病负担。普遍乙型肝炎疫苗免疫、普遍筛查及对所有HBV DNA阳性者治疗，将有助于达到世界卫生组织提出的2030年消除乙型肝炎目标。
- 慢性乙型肝炎 /
- 乙型肝炎疫苗 /
- 治疗学
Abstract:
Among chronic hepatitis B patients eligible for treatment, only 5% have received antiviral therapy worldwide. The strictness of treatment criteria in current guidelines is one of the contributing factors for the low treatment rate of patients with chronic hepatitis B, and expanding the treatment criteria for chronic hepatitis B established in current guidelines may reduce disease burden. Universal hepatitis B vaccination, universal screening, and treatment of all HBV DNA-positive patients will help to achieve the goal of HBV elimination by 2030 proposed by the World Health Organization.
- Hepatitis B, Chronic /
- Hepatitis B Vaccine /
- Therapeutics

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图 1 全球HBV感染和疾病负担(引自参考文献^[1])

Figure 1. Global HBV infection and disease burden (cited from reference^[1])

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图 2 慢性HBV感染者治疗(引自参考文献^[13])

Figure 2. Treatment of patients with chronic HBV infection (cited from reference^[13])

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图 3 慢性HBV感染者4种治疗策略的治疗率(引自参考文献^[14])

Figure 3. Treatment rate of four treatment strategies for patients with chronic HBV infection (cited in reference^[14])

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图 4 3种简化治疗策略比较(引自参考文献^[16])

Figure 4. Comparison of three simplified treatment strategies (cited from reference^[16])

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参考文献(22)

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