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CN 22-1108/R
Volume 38 Issue 7
Jul.  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(7): 1460-1463

Research advances in the diagnosis and treatment of prehepatic noncirrhotic portal hypertension

DOI: 10.3969/j.issn.1001-5256.2022.07.002

  • Department of Gastroenterology, The First Affiliated Hospital of Air Force Medical University, Xi'an 710032, China

Research funding:

National Natural Science Foundation of China (81820108005)

More Information
  • Corresponding author: HAN Ying, hanying@fmmu.edu.cn(ORCID: 0000-0003-3046-9507)
  • Received Date: 2022-04-20
  • Accepted Date: 2022-05-23
  • Published Date: 2022-07-20
    Abstract
  • Prehepatic noncirrhotic portal hypertension is a group of diseases caused by noncirrhotic factors, and currently it is believed that the etiology of these diseases is mainly associated with JAK2 mutation and blood hypercoagulability. Main clinical manifestations include variceal bleeding and splenomegaly, with normal or slightly abnormal liver function. The diagnosis of prehepatic noncirrhotic portal hypertension mainly depends on its imaging characteristics, and meanwhile cirrhotic portal hypertension should be excluded. Anticoagulant therapy and endoscopy are the major therapies for these diseases, and patients often have a good prognosis. This article systematically reviews the recent advances in prehepatic noncirrhotic portal hypertension.

     

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