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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 38 Issue 7
Jul.  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(7): 1662-1666

Research advances in combined non-bioartificial liver in treatment of acute-on-chronic liver failure in adults

DOI: 10.3969/j.issn.1001-5256.2022.07.039

  • Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510635, China

Research funding:

The National Major Science and Technology Project for the Prevention and Treatment of AIDS and Viral Hepatitis (2018ZX10302204-002);

Natural Science Foundation of China (81873572);

Natural Science Foundation of China (82070611);

Sun Yat-Sen University Clinical Research 5010 Program (2020007);

The Five-Year Plan of Third Affiliated Hospital of Sun Yat-Sen University (K00006)

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    Abstract
  • Acute-on-chronic liver failure (ACLF) is a common syndrome of severe liver diseases in clinical practice and has an extremely high short-term mortality rate. Non-bioartificial liver (NBAL) therapy is one of the effective treatment methods for patients with ACLF. In face of the current status of blood supply shortage and changes of treatment concepts, combined NBAL therapy can achieve mutual complementarity and better meet the clinical needs. This article focuses on the clinical application of NBAL in the treatment of ACLF and related research advances and summarizes existing problems and future prospects.

     

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