Highlights of the EASL clinical practice guidelines on sclerosing cholangitis versus the latest Chinese guideline

Xin SUN; Tingyu ZHANG; Yuhao YAO; Ziwei GUO; Jiaxin ZHANG; Yongan YE; Xiaoke LI

doi:10.3969/j.issn.1001-5256.2023.01.007

Volume 39 Issue 1

Jan. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(1): 43-49

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Highlights of the EASL clinical practice guidelines on sclerosing cholangitis versus the latest Chinese guideline

DOI: 10.3969/j.issn.1001-5256.2023.01.007

Xin SUN¹,
Tingyu ZHANG¹,
Yuhao YAO¹,
Ziwei GUO¹,
Jiaxin ZHANG^{1, 2},
Yongan YE^{1, 2
,
,},
Xiaoke LI^{1, 2
,
,}

1.
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
2.
Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing 100700, China

Research funding:

National Natural Science Foundation of China (82174341)

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Corresponding author: YE Yongan, yeyongan@vip.163.com (ORCID: 0000-0001-9765-4665); LI Xiaoke, lixiaoke@vip.163.com (ORCID: 0000-0002-1775-3063)
Received Date: 2022-11-10
Published Date: 2023-01-20

Abstract

Abstract

In 2022, the European Association for the Study of the Liver issued Clinical practice guidelines on sclerosing cholangitis. With reference to the 2017 edition of Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline (2017) and in comparison to the corresponding contents in Guidelines on the diagnosis and management of primary sclerosing cholangitis (2021) issued by Chinese Society of Hepatology, Chinese Medical Association, in 2021, this article summarizes the updates in diagnosis, treatment, monitoring, and management of special populations and analyzes the basis for updated recommendations and their guiding significance in optimizing the clinical management of primary sclerosing cholangitis (PSC). The comparative analysis shows that the new version of the guidelines is similar to the Chinese guidelines in terms of diagnosis, treatment, and follow-up, and it is worth learning from the technical details such as the recommended dose of ursodeoxycholic acid and long-term follow-up plan. Since PSC is a chronic refractory disease, the drugs recommended by current guidelines cannot delay or reverse disease progression, and there is still a lack of consensus statements on immunotherapy and screening protocols for end-stage complications, which might be the directions for further research.
- Primary Sclerosing Cholangitis,
- Diagnosis,
- Therapeutics,
- Surveillance,
- Practice Guidelines as Topic

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References

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Highlights of the EASL clinical practice guidelines on sclerosing cholangitis versus the latest Chinese guideline

DOI: 10.3969/j.issn.1001-5256.2023.01.007

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Highlights of the EASL clinical practice guidelines on sclerosing cholangitis versus the latest Chinese guideline

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