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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 39 Issue 1
Jan.  2023
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Article Contents

Role of pyroptosis in nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2023.01.027
Research funding:

National Natural Science Foundation of China (82000555)

More Information
  • Corresponding author: LI Yue, liyuedl04@126.com (ORCID: 0000-0002-7412-7632)
  • Received Date: 2022-05-02
  • Accepted Date: 2022-07-25
  • Published Date: 2023-01-20
  • As a novel mode of cell death, pyroptosis plays an important role in nonalcoholic fatty liver disease (NAFLD), and the research on pyroptosis may help to explore new therapeutic targets for NAFLD. This article reviews the advances in pyroptosis from the research background and mechanism of pyroptosis and the role of pyroptosis in NAFLD and elaborates on the pyroptosis execution molecules such as GSDME and caspase-11 and the function of inflammasomes including AIM2.

     

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