首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 2014年 9期 => 专家论坛 =>肝脏固有免疫系统研究现状
肝脏固有免疫系统研究现状
Current status of research on liver innate immunity
文章发布日期:2014年08月06日  来源:  作者:叶传涛, 魏欣, 张颖  点击次数:2100次  下载次数:450次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:肝脏固有免疫系统在抵御外来病原体入侵过程中发挥重要作用。叙述了肝脏固有免疫系统抵御病原体入侵的机制,包括肝脏特殊的解剖及生理特征,肝脏固有免疫细胞(肝脏定居细胞和血循环募集细胞)特性及其在病原体入侵过程中发挥功能的机制与相互联系,肝脏固有免疫细胞对病原体的识别及效应机制,肝脏免疫损伤及免疫耐受形成的机制。认为对于肝脏固有免疫细胞及固有免疫分子的研究还需更加深入,进一步了解肝脏作为独立的免疫系统与机体整体的免疫系统之间的联系与区别,将会对肝脏疾病的诊治及更深层次研究有极大的促进作用。
【Abstract】:Liver innate immunity plays an important role in the defense against pathogen invasion. The mechanisms of liver innate immunity for defending against pathogen invasion are reviewed, including the special anatomical and physiological characteristics of the liver, the features of innate immune cells in the liver (liver-settled cells and cells raised from blood circulation) and their function and relationship with each other in pathogen invasion, the process of pathogen identification and effect of liver innate immune cells, and the mechanism of liver immune injury and immune tolerance. Given current research on innate immune cells and innate immune molecules in the liver, further studies should be conducted to understand the connection and difference between liver innate immunity and systemic immunity, thus promoting the diagnosis and treatment of liver diseases and deeper research.
【关键字】:肝疾病;免疫,天然;免疫耐受;超敏反应
【Key words】:liver diseases;immunity, natural;immune tolerance;hypersensitivity
【引证本文】:

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号