首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 2015年 10期 胆汁淤积和胆道疾病 => 胆汁淤积和胆道疾病 =>胆道镜保胆取石术与腹..
胆道镜保胆取石术与腹腔镜胆囊切除术治疗胆囊结石效果比较的Meta分析
Comparison of efficacy between choledochoscopic gallbladder-preserving cholelithotomy and laparoscopic cholecystectomy in treatment of gallstones: a meta-analysis
文章发布日期:2015年09月07日  来源:  作者:樊华,张生军  点击次数:1076次  下载次数:276次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:目的系统评价胆道镜保胆取石术(LRCP)与腹腔镜胆囊切除术(LC)在治疗胆囊结石中各自的优劣性。方法计算机检索中国生物医学文献数据库、中国知网、维普、万方数据库,及PubMed、Embase、the Cochrane Library、Web of Science数据库中有关LRCP与LC治疗胆囊结石的随机对照试验(RCT),截止日期为2015年6月。对纳入的文献进行资料提取和质量评价,采用RevMan5.3软件进行Meta分析。结果共纳入5项RCT,总计685例患者。Meta分析结果显示,LRCL组与LC组在手术时间[比值比(OR)=8.85,95%可信区间(CI):0.49~17.21,P=0.04]及术后腹泻发生率(OR=0.24,95%CI:0.11~0.53,P=0.000 4)方面差异具有统计学意义;而在术中出血量(OR=-12.37,95%CI:-29.73~4.99,P=0.16)、术后肠道功能恢复时间(OR=-7.19,95%CI:-2428~9.90,P=0.41)、住院天数(OR=-0.17,95%CI:-1.98~1.63,P=0.85)、住院费用(OR=-114,95%CI:-2.57~028,P=012)方面差异均无统计学意义。结论LRCP在手术时间及术后腹泻发生率方面要优于LC,而在术中出血量、术后肠道功能恢复时间、住院天数及住院费用方面,两种术式未见明显差别。由于纳入的文献数量有限,且存在发表性偏倚,故需要更多大样本、高质量的RCT来进一步提供有效数据。
【Abstract】:ObjectiveTo systematically evaluate the advantages and disadvantages of choledochoscopic gallbladder-preserving cholelithotomy (CGPC) and laparoscopic cholecystectomy (LC) in the treatment of gallstones. MethodsThe databases of CBM, CNKI, VIP, Wanfang Data, PubMed, EMBASE, the Cochrane Library, and Web of Science were searched for randomized controlled trials (RCTs) related to CGPC and LC in the treatment of gallstones published up to June 2015. Data extraction and quality evaluation were performed for the literature included, and Review Manager 5.3 was used for the meta-analysis. ResultsFive RCTs involving 685 patients were included. The results of the meta-analysis showed that CGPC group and LC group had significant differences in operation time (OR=8.85, 95% CI: 049-17.21, P=0.04) and incidence of postoperative diarrhea (OR=0.24, 95% CI: 0.11-0.53, P=0.000 4). However, no significant differences were seen between the two groups in intraoperative bleeding volume (OR=-12.37, 95% CI: -29.73-4.99, P=0.16), time to postoperative intestinal function recovery (OR=-7.19, 95% CI: -24.28-9.90, P=0.41), hospitalization days (OR=-0.17, 95% CI: -1.98-1.63, P=0.85), and hospital costs (OR=-1.14, 95% CI: -2.57-0.28, P=0.12). ConclusionThe operation time and incidence of postoperative diarrhea in CGPC are superior to those in LC, while no significant differences are observed in intraoperative bleeding volume, time to postoperative intestinal function recovery, hospitalization days, and hospital costs. Due to a limited number of articles included and publication bias, RCTs with a large sample size and high quality are needed to provide more effective data.
【关键字】:胆囊结石病;胆道镜;胆囊切除术,腹腔镜;Meta分析
【Key words】:cholecystolithiasis; choledochoscopy; cholecystectomy, laparoscopic; Meta-analysis
【引证本文】:樊华, 张生军. 胆道镜保胆取石术与腹腔镜胆囊切除术治疗胆囊结石效果比较的Meta分析[J]. 临床肝胆病杂志, 2015, 31(10): 1665-1670.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号