首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 2017年 9期重症肝病 => 专家论坛 =>生物人工肝和肝移植:肝衰竭治疗新..
生物人工肝和肝移植:肝衰竭治疗新模式
Bioartificial liver and liver transplantation: new modalities for the treatment of liver failure
文章发布日期:2017年08月04日  来源:  作者:丁义涛  点击次数:1531次  下载次数:255次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:肝衰竭的主要特征是肝细胞大范围坏死,病情进展迅速且预后差,目前治疗缺乏特效药物和手段。归纳了肝衰竭的4种治疗手段:内科治疗、细胞移植、肝移植和人工肝支持治疗,并就现有的治疗手段进行阐述分析。目前内科治疗方案有待优化,细胞移植治疗尚未应用于临床,肝移植是最有效的手段,但供肝短缺、费用昂贵,人工肝可以有效清除患者体内毒性物质。因此提出人工肝作为肝移植的过渡治疗,可以为肝再生或者肝移植争取时间,延长患者生存期,具有良好的应用前景。生物人工肝联合肝移植的新模式,可以为肝衰竭患者带来福音。
【Abstract】:The main features of liver failure are extensive necrosis of hepatocytes, rapid disease progression, and poor prognosis, and at present, there are no effective drugs and methods for the treatment of liver failure. This article summarizes four treatment methods for liver failure, i.e., medical treatment, cell transplantation, liver transplantation, and artificial liver support therapy, and elaborates on the existing treatment methods. The current medical treatment regimen should be optimized; cell transplantation has not been used in clinical practice; liver transplantation is the most effective method, but it is limited by donor liver shortage and high costs; artificial liver can effectively remove toxic substances in human body. Therefore, this article puts forward artificial liver as a transition for liver transplantation; artificial liver can buy time for liver regeneration or liver transplantation and prolong patients′ survival time and thus has a promising future. The new treatment modality of bioartificial liver combined with liver transplantation may bring good news to patients with liver failure.
【关键字】:肝功能衰竭; 肝移植; 肝, 人工; 治疗
【Key words】:liver failure; liver transplantation; liver, artificial; therapy
【引证本文】:丁义涛. 生物人工肝和肝移植: 肝衰竭治疗新模式[J]. 临床肝胆病杂志, 2017, 33(9): 1693-1698.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号