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ALT正常的慢性HBV感染者临床病理特征
Research advances in clinicopathological features of patients with chronic HBV infection and normal alanine aminotransferase level
文章发布日期:2017年08月04日  来源:  作者:李艳平,李春艳,陈延平  点击次数:1127次  下载次数:320次

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【摘要】:通常认为ALT正常的慢性HBV感染者无或仅有轻微的肝组织病理改变,然而近年来大量研究发现,ALT正常的慢性HBV感染者其肝组织病理亦出现明显的炎症和纤维化改变。对ALT正常的慢性HBV感染者临床特征与肝组织病理特征的关系进行论述,认为年龄、性别、HBeAg状态、HBV DNA载量、ALT水平以及肝脏硬度测量值与其肝组织病理特征的改变均有关系,监测上述临床指标有助于及早发现ALT正常的慢性HBV感染者的肝组织病理改变。
【Abstract】:It was generally considered that patients with chronic HBV infection and normal alanine aminotransferase (ALT) level had no or mild liver pathological changes, but in recent years, a large number of studies have found that such patients may also have marked inflammation and fibrosis in the liver. This article discusses the association between clinical features and liver pathological features in patients with chronic HBV infection and normal ALT level and points out that age, sex, HBeAg status, HBV DNA load, ALT level, and liver stiffness measurement are associated with liver pathological changes. Monitoring of these clinical indices helps with early detection of liver pathological changes in patients with chronic HBV infection and normal ALT level.
【关键字】:肝炎病毒,乙型;肝炎,乙型,慢性;综述
【Key words】:hepatitis B virus; hepatitis B, chronic; review
【引证本文】:李艳平, 李春艳, 陈延平. ALT正常的慢性HBV感染者临床病理特征[J]. 临床肝胆病杂志, 2017, 33(8): 1568-1571.

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