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【摘要】：门静脉系统血栓（PVT）指门静脉或其分支血管内形成血栓，可导致门静脉高压，引起一系列病理生理变化。PVT通常是由多种病因引起的，主要包括血液高凝状态、门静脉流速降低和血管内皮损伤等。主要探讨了PVT的发病机制，指出临床上应对PVT患者的病因进行全面评估，以协助治疗。
【Abstract】：Portal vein thrombosis (PVT) refers to the process of thrombosis in the portal vein or its branches and can lead to portal hypertension and a series of pathophysiological changes. PVT is often caused by various etiologies, including hypercoagulable state, reduced portal flow velocity, and vascular endothelial injury. This article reviews the mechanisms of the development and progression of PVT and points out that the etiology of PVT should be evaluated comprehensively to assist treatment.
【关键字】：静脉血栓形成； 门静脉； 危险因素
【Key words】：venous thrombosis; portal vein; risk factors
【引证本文】：YANG YY, WANG XY. Mechanisms of the development and progression of portal vein thrombosis［J］. J Clin Hepatol, 2018, 34(10): 2063-2068. （in Chinese)
羊媛苑， 王晓艳. 门静脉系统血栓的发生发展机制［J］. 临床肝胆病杂志, 2018, 34(10): 2063-2068.