首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 2018年 10期 门静脉栓塞的基础与临床 => 综述 =>孕期服用抗病毒药物阻断HBV..
孕期服用抗病毒药物阻断HBV母婴传播的研究进展
Research advances in the application of antiviral drugs during pregnancy for blocking mother-to-child transmission of hepatitis B virus
文章发布日期:2018年09月10日  来源:  作者:王慧娟,段钟平,张桓虎,等  点击次数:292次  下载次数:37次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:母婴垂直传播是慢性乙型肝炎患者感染HBV的主要途径,HBV感染率随着母亲携带HBV病毒量的增加逐步升高。虽然目前新生儿主被动免疫预防已基本实施,但HBV母婴垂直传播率仍在10%左右。孕妇高病毒载量时应在孕期采取抗病毒治疗,降低病毒量,从而预防及阻断HBV母婴传播,减少慢性乙型肝炎的发病率。通过检索国内外文献详细描述了抗病毒药物在孕期使用的安全性及有效性,为日后指导孕期服药提供依据。
【Abstract】:Mother-to-child vertical transmission is an important route of transmission for hepatitis B virus (HBV) infection in patients with chronic hepatitis B, and the rate of HBV infection increases with the increase in the mother′s HBV viral load. Although active and passive immunoprophylaxis has been implemented for neonates at present, the rate of mother-to-child vertical transmission of HBV remains around 10%. Therefore, pregnant women with a high viral load should receive antiviral therapy to reduce the viral load, in order to prevent and block the mother-to-child transmission of HBV and reduce the incidence rate of chronic hepatitis B. By retrieving related literature in China and foreign countries, this article describes the safety and efficacy of antiviral agents during pregnancy and provides a reliable basis for guiding medication during pregnancy.
【关键字】:肝炎病毒, 乙型; 疾病传播, 垂直; 抗病毒药; 综述
【Key words】:hepatitis B virus; disease transmission, vertical; antiviral agents; review
【引证本文】:WANG HJ, DUAN ZP, ZHANG HH, et al. Research advances in the application of antiviral drugs during pregnancy for blocking mother-to-child transmission of hepatitis B virus[J]. J Clin Hepatol, 2018, 34(10): 2208-2212. (in Chinese)
王慧娟, 段钟平, 张桓虎, 等. 孕期服用抗病毒药物阻断HBV母婴传播的研究进展[J]. 临床肝胆病杂志, 2018, 34(10): 2208-2212.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号