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胰腺内副脾误诊2例报告
DOI: 10.12449/JCH240223
伦理学声明：本例报告已获得患者及家属知情同意。
利益冲突声明：本文不存在任何利益冲突。
作者贡献声明：张孟哲负责收集病例资料，撰写文章并最后定稿；饶洁参与收集病例资料，资料分析；张正乐负责拟定写作思路，修改论文。
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摘要: 副脾是指正常脾脏以外存在的，与主脾结构相似，有一定功能的脾脏组织，其中完全被胰腺包裹的胰腺内副脾（IPAS）发生率仅为2%，因其临床症状不典型，影像学特征与胰腺神经内分泌肿瘤、胰腺实性假乳头状瘤以及其他胰腺占位性病变较为相似，临床上容易误诊。本文报道了2例分别被误诊为胰腺神经内分泌肿瘤和胰腺实性假乳头状瘤的IPAS患者，并分析误诊原因，总结诊疗经验，以期提升临床对IPAS明确鉴别诊断的认识。Abstract: Accessory spleen refers to the spleen tissue that exists outside of the normal spleen， with a similar structure to the main spleen and certain functions. Intrapancreatic accessory spleen （IPAS） completely enveloped by the pancreas has an incidence rate of only 2%， and it is easily misdiagnosed in clinical practice due to its atypical clinical symptoms and similar radiological features to pancreatic neuroendocrine tumor， pancreatic solid pseudopapillary tumor， and other pancreatic space-occupying lesions. This article reports the clinical data of two patients with IPAS who were misdiagnosed as pancreatic neuroendocrine tumor and pancreatic solid pseudopapillary tumor， respectively， analyzes the reasons for misdiagnosis， and summarizes the experience in diagnosis and treatment， in order to improve the ability for the differential diagnosis of IPAS in clinical practice.
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Key words:
- Splenic Diseases /
- Pancreas /
- Diagnostic Errors /
- Neuroendocrine Tumors /
- Papilloma
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图 1 病例1患者术前CT扫描结果
注： a，平扫期；b，动脉期；c，静脉期。胰腺尾部可见大小为0.8 cm×0.7 cm的结节样异常强化影，平扫期显示不清，动脉期明显强化，静脉期呈稍高强化，且动脉期和静脉期强化程度均高于胰腺组织（红色箭头）。
Figure 1. Preoperative CT scan of patient 1
图 3 病例1患者术后病理结果（HE染色，×100）
Figure 3. Postoperative pathology of patient 1（HE staining，×100）
图 4 病例2患者术前胰腺钩突部占位CT扫描
注： a，平扫期；b，动脉期；c，静脉期。胰腺钩突部不规稍低密度影，大小为2.7 cm×3.1 cm，增强扫描呈弱强化，边缘不规则，紧贴肠系膜上静脉，与十二指肠水平段分界不清（红色箭头）。
Figure 4. Preoperative pancreatic uncinate process space occupying CT scan of patient 2
图 5 病例2患者术前胰腺尾部占位CT扫描
注： a，平扫期；b，动脉期；c，静脉期。平扫期可见胰尾部直径3 cm的类圆形稍低密度影，动脉期和静脉期扫描轻度不均匀强化，边缘可见钙化（红色箭头）。
Figure 5. Preoperative pancreatic tail space occupying CT scan of patient 2
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