内分泌指标及超声检查在小儿胰腺损伤早期诊断中的应用

金明均; 孙溶涓; 董亮; 詹江华

doi:10.12449/JCH240335

内分泌指标及超声检查在小儿胰腺损伤早期诊断中的应用

DOI: 10.12449/JCH240335

金明均^{1, 2},
孙溶涓^{1, 3},
董亮^{1, 3},
詹江华^{1, 3, , ,}

1.
天津市儿童医院（天津大学儿童医院）外科，天津 300074
2.
天津市儿童出生缺陷防治重点实验室，天津 300134
3.
天津医科大学研究生院，天津 300070

基金项目:

天津市公共卫生科技重大专项 (21ZXGWSY00070);

天津市应用基础研究项目 (22JCZDJC00290);

新疆维吾尔自治区自然科学基金 (2022D01A27);

新疆维吾尔自治区自然科学基金 (2021D01A38)

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：金明均、孙溶涓负责撰写论文；董亮、詹江华参与修改论文；詹江华负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
詹江华， zhanjianghuatj@163.com （ORCID： 0000-0002-5257-8619）

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出版历程
- 收稿日期: 2023-06-17
- 录用日期: 2023-09-08
- 出版日期: 2024-03-20

Application of endocrine indices and ultrasound examination in the early diagnosis of pediatric pancreatic injury

Mingjun JIN^{1, 2},
Rongjuan SUN^{1, 3},
Liang DONG^{1, 3},
Jianghua ZHAN^{1, 3
, ,
,}

1.
Department of Surgery，Tianjin Children’s Hospital/Children’s Hospital of Tianjin University，Tianjin 300074，China
2.
Tianjin Key Laboratory of Birth Defects for Prevention and Treatment，Tianjin 300134
3.
Graduate School，Tianjin Medical University，Tianjin 300070，China

Research funding:

Tianjin Science and Technology Bureau Special Project (21ZXGWSY00070);

Tianjin Applied Basic Research Project (22JCZDJC00290);

Xinjiang Uygur Autonomous Region Science Foundation Project (2022D01A27);

Xinjiang Uygur Autonomous Region Science Foundation Project (2021D01A38)

More Information

Corresponding author: ZHAN Jianghua， zhanjianghuatj@163.com （ORCID： 0000-0002-5257-8619）

摘要

摘要: 腹部外伤的发生率在小儿创伤中占比逐年增加，创伤性胰腺损伤应引起临床医生的足够重视。胰腺位于腹膜后，尤其是Ⅰ、Ⅱ级损伤的患儿，其早期诊断较为困难。本文通过文献复习，分析内分泌指标及腹部超声检查在小儿胰腺损伤早期诊断中的价值，以提高早诊率，避免相关并发症的发生。内分泌指标中血清胰岛素、C肽等指标的变化，对于诊断和评估小儿胰腺损伤有一定的优势，可作为小儿胰腺损伤病情的预警指标。超声弹性成像技术为胰腺损伤的诊断和鉴别提供了新的方法；而对比增强超声在识别患儿胰腺损伤中具有较高的特异度及敏感度，由于其无放射性损害，有望成为CT检查的替代方案。
- 腹部损伤 /
- 胰腺 /
- 儿童 /
- 早期诊断
Abstract: The incidence rate of abdominal trauma is increasing year by year in pediatric trauma， and traumatic pancreatic injury should be taken seriously by clinicians. The pancreas is located behind the peritoneum， and it is difficult to make an early diagnosis of pancreatic injury， especially in children with grade ‍Ⅰ‍/Ⅱ injury. Through a literature review， this article analyzes the application value of endocrine indices and abdominal ultrasound in the early diagnosis of pediatric pancreatic injury， so as to improve the rate of early diagnosis and avoid the onset of related complications. Changes of the endocrine indices such as serum insulin and C Peptide have certain advantages in diagnosing and evaluating the degree of pediatric pancreatic injury and can thus be used as early warning indices for pediatric pancreatic injury. Ultrasound elastography provides a new method for the diagnosis and differentiation of pancreatic injury； contrast-enhanced ultrasound， which has no radioactive damage， has relatively high specificity and sensitivity in identifying pediatric pancreatic injury， and therefore， it is expected to become an alternative to CT examination.
- Abdominal Injuries /
- Pancreas /
- Child /
- Early Diagnosis

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参考文献(38)

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