几丁质酶样蛋白40与肝纤维化的关系

史佳伟; 黄晶

doi:10.3969/j.issn.1001-5256.2021.09.040

几丁质酶样蛋白40与肝纤维化的关系

DOI: 10.3969/j.issn.1001-5256.2021.09.040

史佳伟,
黄晶^,

吉林大学第一医院检验科，长春 130021

基金项目:

吉林省科技厅重点研发项目 (20200404167YY)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：史佳伟负责提出研究选题，调研整理文献，起草论文，修改论文；黄晶负责指导撰写文章并最后定稿。

详细信息

通信作者:
黄晶，jluhuangjing1@126.com

中图分类号: R575.2
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- 文章访问数: 417
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- 被引次数: 0
出版历程
- 收稿日期: 2021-01-25
- 录用日期: 2021-04-28
- 出版日期: 2021-09-20

Association between YKL-40 and liver fibrosis

Jiawei SHI,
Jing HUANG^,

Department of Clinical Laboratory, The First Hospital of Jilin University, Changchun 130021, China

Research funding:

Jilin Province Science and Technology Development Program （20200404167YY）

摘要

摘要: 几丁质酶样蛋白40(YKL-40)是一种新兴的炎性标志物，肝脏表达水平最高。总结了YKL-40作为肝脏纤维化血清学标志物的研究进展。分析表明YKL-40能够有效评估肝脏纤维化的严重程度，具有良好的临床应用前景。由于单一指标诊断效能有限，建立YKL-40诊断模型与其他血清学指标联合应用将是未来的研究热点。
- 几丁质酶样蛋白40 /
- 肝硬化 /
- 生物标记
Abstract: YKL-40 is an emerging inflammatory marker with the highest expression level in the liver. This article summarizes the research advances in YKL-40 as a serological marker for liver fibrosis. The analysis shows that YKL-40 can effectively evaluate the severity of liver fibrosis and thus holds promise for clinical application. Due to limited diagnostic efficiency of a single index, the combination of YKL-40 diagnostic model and other serological markers will become a research hotspot in the future.
- YKL-40 /
- Liver Cirrhosis /
- Biomarkers

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参考文献(38)

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