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微小RNA在胆管癌发生发展中的作用

陈圣 陈国想 何中明 程树杰 赵继森

引用本文:
Citation:

微小RNA在胆管癌发生发展中的作用

DOI: 10.3969/j.issn.1001-5256.2021.09.048
基金项目: 

保定市科技计划项目 (2041ZF319)

利益冲突声明: 所有作者均声明不存在利益冲突。
作者贡献声明: 陈圣负责课题设计, 资料分析, 撰写论文;陈国想、何中明参与收集数据, 修改论文;程树杰、赵继森负责拟定写作思路, 指导撰写文章并最后定稿。
详细信息
    通信作者:

    赵继森, cheng66142@163.com

  • 中图分类号: R735.8

Role of miRNA in the development and progression of cholangiocarcinoma

Research funding: 

Baoding Science and Technology Program (2041ZF319)

  • 摘要: 胆管癌是最为常见的胆道恶性肿瘤, 具有较高的死亡率, 且其发病率逐年上升。早期症状不典型和复杂的解剖位置, 常常导致胆管癌患者难以早期得到确诊, 错过最佳治疗时期, 预后不良。近年来, miRNA被证明在胆管癌发生发展的病理生理过程中起着关键作用。简述了miRNA在胆管癌的发生、侵袭和转移、耐药、肿瘤微环境中的调节作用, 并介绍了外泌体miRNA与胆管癌相关的新进展, 以期为胆管癌提供潜在的治疗策略。

     

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  • 收稿日期:  2021-01-20
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