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骨形态发生蛋白4在非酒精性脂肪性肝病发病机制中的作用

王宇威 刘近春 柴茹

引用本文:
Citation:

骨形态发生蛋白4在非酒精性脂肪性肝病发病机制中的作用

DOI: 10.3969/j.issn.1001-5256.2023.05.027
基金项目: 

山西省科技成果转化引导专项项目 (201904D131030)

利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:王宇威负责收集文献,撰写论文;柴茹负责收集、筛选文献;刘近春负责拟定写作思路,指导撰写文章并最后定稿。
详细信息
    通信作者:

    刘近春,zxr610624@163.com (ORCID: 0000-0002-1984-6802)

Role of bone morphogenetic protein-4 in the pathogenesis of nonalcoholic fatty liver disease

Research funding: 

Transformation of Scientific and Technological Achievements Special Guide Project of Shanxi Province (201904D131030)

More Information
  • 摘要: 非酒精性脂肪性肝病(NAFLD)目前已成为全球最常见的慢性肝病之一,严重危害人类健康。近年来研究发现骨形态发生蛋白4(BMP4)与NAFLD之间可能存在一定相关性。本综述旨在依据国内外关于BMP4与NAFLD相关研究的最新进展,探究BMP4作用于NAFLD的潜在机制,以期为NAFLD的预防及治疗提供新的思路。

     

  • 图  1  BMP4在NAFLD发病中的作用机制示意图

    注:M1,M1型巨噬细胞;M2,M2型巨噬细胞。

    Figure  1.  Mechanism of BMP4 in the pathogenesis of NAFLD

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  • 收稿日期:  2022-09-20
  • 录用日期:  2022-10-21
  • 出版日期:  2023-05-20
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