巨细胞病毒性肝炎研究进展

曾庆贺; 孟艳; 李玉香

doi:10.3969/j.issn.1001-5256.2023.06.028

巨细胞病毒性肝炎研究进展

DOI: 10.3969/j.issn.1001-5256.2023.06.028

曾庆贺¹,
孟艳²,
李玉香^3, , ,

1.
枣庄市妇幼保健院感染科，山东枣庄 277100
2.
枣庄职业学院医学院，山东枣庄 277800
3.
吉林大学第一医院感染症科，长春 130021

基金项目:

山东省医药卫生科技发展计划项目 (2015WS0012)

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：曾庆贺负责文章撰写；孟艳协助文章修改；李玉香负责指导文章及最终定稿。

详细信息

通信作者:
李玉香, yuxiangli612@126.com (ORCID: 0000-0002-4191-2271)

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出版历程
- 收稿日期: 2022-09-23
- 录用日期: 2022-11-04
- 出版日期: 2023-06-20

Research advances in cytomegalovirus hepatitis

Qinghe ZENG¹,
Yan MENG²,
Yuxiang LI^{3
, ,
,}

1.
Department of Infectious Diseases, Zaozhuang Maternal and Child Health Hospital, Zaozhuang, Shandong 277100, China
2.
School of Medicine, Zaozhuang Vocational College, Zaozhuang, Shandong 277800, China
3.
Department of Infectious Diseases, The First Hospital of Jilin University, Changchun 130021, China

Research funding:

Projects of Medical and Health Technology Development Program in Shandong Province (2015WS0012)

More Information

Corresponding author: LI Yuxiang, yuxiangli612@126.com (ORCID: 0000-0002-4191-2271)

摘要

摘要: 巨细胞病毒性肝炎是由人巨细胞病毒感染引起的，儿童和免疫功能低下肝病人群中最常见的一种肝脏疾病。该病无特异性表现，临床上易与其他病毒性肝炎混淆，导致失治误治。巨细胞病毒性肝炎的早期诊断至关重要，以便给予及时有效治疗，合理选择抗病毒药物及疗程。本文对巨细胞病毒性肝炎的病原学、流行病学、发病机制及临床表现、诊断治疗及预防的近年研究进展作一综述。
- 巨细胞病毒感染 /
- 肝炎, 病毒性, 人 /
- 流行病学 /
- 病理状态, 体征和症状 /
- 诊断 /
- 治疗学
Abstract: Cytomegalovirus hepatitis is a liver disease caused by human cytomegalovirus infection and is one of the most common liver diseases in children and immunocompromised individuals. This disease has no specific clinical manifestations and is easily confused with other types of viral hepatitis, which may lead to delayed treatment or mistreatment. Therefore, the early diagnosis of cytomegalovirus hepatitis is of vital importance, and patients should be given timely and effective treatment with appropriately selected antiviral drugs and course of treatment. This article reviews the recent research advances in the etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis, treatment, and prevention of cytomegalovirus hepatitis.
- Cytomegalovirus Infections /
- Hepatitis, Viral, Human /
- Epidemiology /
- Pathological Conditions, Signs and Symptoms /
- Diagnosis /
- Therapeutics

HTML全文

图 1 CMV感染后肝脏炎症产生机制

注：PDGFRA，血小板衍生生长因子受体；NRP-2，神经纤毛蛋白-2。

Figure 1. Mechanism of liver inflammation after cytomegalovirus infection

下载: 全尺寸图片幻灯片

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