The Oddi sphincter has a delicate structure,and the integrity of its function has an irreplaceable role in preventing retrograde infection due to the reflux of duodenal contents and bacteria and maintaining the balance of physiological environment inside and outside the liver,the pancreas,and the gallbladder. Endoscopic sphincterotomy impairs the integrity of the Oddi sphincter,and such negative effects have received more and more attention. This article reviews the research advances in the impairment of Oddi sphincter function caused by endoscopic sphincterotomy and points out that clinicians should understand and attach importance to such impairment,perform a comprehensive analysis from various aspects,and develop reasonable diagnosis and treatment regimens based on patient's own conditions.
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