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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 37 Issue 4
Apr.  2021
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Article Navigation >  Journal of Clinical Hepatology  > 2021  >  37(4): 969-972

Effect of hypothyroidism on chronic liver diseases

DOI: 10.3969/j.issn.1001-5256.2021.04.054

  • Department of Chronic Liver Diseases, Tianjin Second People's Hospital, Tianjin 300192, China

  • Received Date: 2020-09-25
  • Accepted Date: 2020-10-22
  • Published Date: 2021-04-20
    Abstract
  • The liver plays an important role in the metabolism, degradation, and excretion of thyroid hormones in the normal physiological state; however, when liver injuries occur, there is a significance increase in hypothyroidism, and most patients have no obvious clinical symptoms or signs. The article summarizes the chronic liver diseases caused by various etiologies and the change in thyroid function in different stages of disease and points out that the reduction in the level of thyroid hormone has an important value in predicting the risk, condition, and prognosis of chronic liver diseases. Studies have shown that some patients with chronic liver diseases can improve the condition and prognosis by adjusting thyroid function. In addition, a series of genetic disorders or dysfunctions caused by abnormal thyroid metabolism may become new therapeutic targets for certain chronic liver diseases, which needs to be confirmed by further studies.

     

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