Advances in investigational new drugs for nonalcoholic fatty liver disease

Kun XU; Xu ZHANG; Ying LI; Zhenbin HU

doi:10.3969/j.issn.1001-5256.2021.07.047

Volume 37 Issue 7

Jul. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(7): 1699-1703

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Advances in investigational new drugs for nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2021.07.047

Kun XU¹,
Xu ZHANG¹,
Ying LI¹,
Zhenbin HU^{2
,
,}

1.
Graduate School of Guangxi University of Chinese Medicine, Nanning 530222, China
2.
First Ward of Hepatology, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, China

Research funding:

The National Thirteenth Five-Year Plan"Prevention and Treatment of Major Infectious Diseases such as AIDS and Viral Hepatitis" Science and Technology Major Special Fund Project (2018ZX10725505-002)

Received Date: 2020-11-23
Accepted Date: 2021-01-11
Published Date: 2021-07-20

Abstract

Abstract

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and is closely associated with obesity, insulin resistance, and other metabolic diseases. There are currently no drugs approved for treatment, and routine lifestyle management can hardly have a positive impact on this disease. This article reviews the investigational new drugs for NAFLD, including metabolic regulators, anti-inflammatory antioxidants, and anti-fibrosis agents, and summarizes the results of their clinical studies, so as to provide new ideas for the clinical treatment of NAFLD and the and development of related drugs.
- Nonalcoholic Fatty Liver Disease,
- Drugs, Investigational,
- Antioxidants

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References(43)

References

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Advances in investigational new drugs for nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2021.07.047

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Advances in investigational new drugs for nonalcoholic fatty liver disease

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