Considerations on the elevation of aminotransferases in primary biliary cholangitis

Mingli HU; Qixia WANG; Xiong MA

doi:10.3969/j.issn.1001-5256.2021.10.005

Volume 37 Issue 10

Oct. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(10): 2277-2279

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Considerations on the elevation of aminotransferases in primary biliary cholangitis

DOI: 10.3969/j.issn.1001-5256.2021.10.005

Shanghai Institute of Digestive Disease, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China

Research funding:

National Natural Science Foundation of China (82070581);

National Natural Science Foundation of China (81790634)

Received Date: 2021-09-12
Accepted Date: 2021-09-12
Published Date: 2021-10-20

Abstract

Abstract

Primary biliary cholangitis (PBC) is an autoimmune-mediated chronic cholestatic liver disease, with the typical biochemical manifestation of significantly elevated alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (GGT), with or without mild-to-moderate elevation of aminotransferases. ALP and GGT play an important role in the diagnosis and monitoring of PBC. With a deeper understanding of PBC, the significance of elevated aminotransferases in diagnosis and treatment has attracted more and more attention. This article briefly summarizes the significance of elevation of aminotransferases in PBC patients.
- Liver Cirrhosis, Biliary,
- Transaminases,
- Autoimmune Diseases

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References(21)

References

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Considerations on the elevation of aminotransferases in primary biliary cholangitis

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Considerations on the elevation of aminotransferases in primary biliary cholangitis

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