中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 37 Issue 11
Nov.  2021
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Article Contents

Mechanism of autophagy in the development and progression of autoimmune hepatitis

DOI: 10.3969/j.issn.1001-5256.2021.11.044
Research funding:

National Natural Science Foundation of China (82003994);

Henan Province Traditional Chinese Medicine Research Project (2019JDZX2034)

  • Received Date: 2021-03-01
  • Accepted Date: 2021-03-26
  • Published Date: 2021-11-20
  • Autophagy is a process of self-defense and self-repair of cells and tissues and plays an important role in regulating the body's immune inflammatory response and maintaining the homeostasis of liver cells. This article summarizes the mechanism of autophagy in the development and progression of autoimmune hepatitis (AIH) from the aspects of the role of autophagy in regulating immune inflammatory response, regulating immune signal transduction, and preventing overactivated innate immune response. It is believed that autophagy may reveal the mechanism of AIH and provide new ideas and methods for the research on AIH.

     

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    汪永强, 李显勇, 杨琳, 等. 自身免疫肝炎患者外周血PBMCs自噬基因表达及Th17/CD4+CD25+CD127lowTreg细胞与肝脏功能相关性研究[J]. 中国实验诊断学, 2020, 24(6): 934-940. DOI: 10.3969/j.issn.1007-4287.2020.06.013.
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