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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 32 Issue 1
Jan.  2016
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Article Contents

Research advances in mouse models of hepatitis B virus infection

DOI: 10.3969/j.issn.1001-5256.2016.01.036
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  • Received Date: 2015-05-04
  • Published Date: 2016-01-20
  • Hepatitis B virus( HBV) is a great threat to human health,but due to its strong species specificity,there are still no ideal animal models at present to clarify the pathogenesis of HBV infection. At present,the research on HBV infection models mainly concentrates on mice,and great progress has been achieved / made. This review focuses on the advantages and disadvantages of HBV transgenic mouse model,HBV- transfected mouse model,and human- mouse chimeric liver HBV mouse model,and suggests that rational application of these models helps to clarify the pathogenesis of HBV.

     

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