肝移植术后中远期并发症的防治任务与策略

刘懿禾; 郑虹; 沈中阳

doi:10.3969/j.issn.1001-5256.2019.11.002

肝移植术后中远期并发症的防治任务与策略

DOI: 10.3969/j.issn.1001-5256.2019.11.002

天津市第一中心医院器官移植中心中国医学科学院移植医学重点实验室国家卫生健康委员会危重病急救医学重点实验室天津市器官移植重点实验室

基金项目:

天津市器官移植临床医学研究中心项目(15ZXLCSY00070)；中国医学科学院中央级公益性科研院所基本科研业务费专项资金(2019PT320016)；

详细信息

中图分类号: R657.3
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出版历程
- 收稿日期: 2019-10-08
- 出版日期: 2019-11-20

Tasks and strategies for the prevention and treatment of middle-and long-term complications after liver transplantation

Center of Organ Transplantation,Tianjin First Center Hospital,Key Laboratory of Transplant Medicine,Chinese Academy of Medical Sciences,Key Laboratory of National Health Commission for Critical Care and Emergency Medicine,Tianjin Key Laboratory for Organ Transplantation

Research funding:

摘要

摘要: 随着肝移植技术的持续改进及关联学科领域创新成果的涌现与借鉴,肝移植术后中远期并发症在病因构成与临床转归等方面正在悄然迁变,其防治对策值得探究与调整。近年,防治肝炎复发等移植后并发症取得了突破性进展,但应加强规范化诊疗,以使移植受者最大程度获益。迄今,防治发病机制不明及成因复杂的肝移植术后中远期并发症,仍主要依赖于针对相关风险因素的长期监测与防控。维护移植肝功能、控制原发病复发、防治新发疾病及接续治疗术前并存疾病,是实施肝移植受者长期管理的主要任务方向。以此为线索,概括阐述了当前肝移植术后中远期并发症的防治任务与策略。
- 肝移植 /
- 手术后并发症 /
- 治疗学
Abstract: With the continuous improvement of liver transplantation techniques and the innovation of related disciplines,great changes have been observed in the etiology and clinical outcome of middle-and long-term complications after liver transplantation,and thus related prevention and treatment strategies are worthy of exploration and adjustment. In recent years,breakthroughs have been made in the prevention and treatment of post-transplantation complications including the recurrence of hepatitis,but standardized diagnosis and treatment should be strengthened in order to maximize the benefits of recipients. So far,the prevention and treatment of middle-and long-term complications with unknown pathogenesis and complicated causes after liver transplantation still rely on the long-term monitoring,prevention,and control of related risk factors. The main tasks of long-term management of liver transplantation recipients is to maintain the function of transplanted liver,control the recurrence of primary diseases,prevent and treat the new-onset diseases,and continue to treat the concomitant diseases before surgery. This article elaborates on the tasks and strategies for the prevention and treatment of middle-and long-term complications after liver transplantation.
- liver transplantation /
- postoperative complications /
- therapeutics

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参考文献(29)

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