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Volume 41 Issue 8
Aug.  2025
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Article Navigation >  Journal of Clinical Hepatology  > 2025  >  41(8): 1668-1672

Research advances in the genetic mechanism of autoimmune hepatitis

DOI: 10.12449/JCH250830

  • Department of Infectious Diseases，Guang’anmen Hospital，China Academy of Chinese Medical Sciences，Beijing 100053，China

Research funding:

Science and Technology Innovation Project of China Academy of Chinese Medical Sciences (CI2021A00801)

More Information
  • Corresponding author: LYU Wenliang， lvwenliang@sohu.com （ORCID： 0000-0002-4552-919X）
  • Received Date: 2024-12-10
  • Accepted Date: 2025-02-11
  • Published Date: 2025-08-25
    Abstract
  • Autoimmune hepatitis （AIH） is a chronic inflammatory liver disease caused by immune abnormalities. Genetic factors play an important role in AIH. The analysis of genes has shown that new genetic markers can help to deepen the understanding of the risk of AIH and develop treatment measures. This article reviews the research advances in human leukocyte antigen， single nucleotide polymorphism， and epigenetics， in order to provide a reference for clinical treatment and research on AIH.

     

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