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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 2
Feb.  2016
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Research advances in portal hypertensive gastropathy

DOI: 10.3969/j.issn.1001-5256.2016.02.035
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  • Received Date: 2015-08-21
  • Published Date: 2016-02-20
  • Portal hypertensive gastropathy( PHG) is a disease caused by cirrhotic( or non- cirrhotic) portal hypertension,with a typical feature of snake- skin appearance of the gastric mucosa under endoscope. Many studies have shown that portal hypertension is a necessary condition for the development and progression of PHG. PHG is often complicated by acute or chronic upper gastrointestinal bleeding,which may be the direct reason for patients to visit the hospital. Therefore,the study of the diagnosis and treatment of PHG is very important in clinical practice. This article reviews the research advances in the pathogenesis,classification,diagnosis,and treatment of PHG.

     

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  • [1]LEE TH,JANG JY,JEONG SW,et al.Gastric polyposis associated with portal hypertension[J].Korean J Intern Med,2013,28(2):261.
    [2]KARKI L,GORKHLY MP,KARKI BB,et al.Study of upper gastrointestinal tract endoscopic findings in portal hypertension[J].JNMA J Nepal Med Assoc,2013,52(190):337-342.
    [3]MATSUSHITA Y,NARAHARA Y,FUJIMORI S,et al.Effects of transjugular intrahepatic portosystemic shunt on changes in the small bowel mucosa of cirrhotic patients with portal hypertension[J].J Gastroenterol,2012,48(5):633-639.
    [4]ZARDI EM,GHITTONI G,MARGIOTTA D,et al.Portal hypertensive gastropathy in cirrhotics without varices:a case-control study[J].Eur J Gastroenterol Hepatol,2015,27(1):91-96.
    [5]KINJO N,YANO H,SUGIMACHI K,et al.Large simple hepatic cysts leading to gastric fundal varices in a noncirrhotic patient[J].Fukuoka Igaku Zasshi,2013,104(11):449-455.
    [6]SIRAMOLPIWAT S.Transjugular intrahepatic portosystemic shunts and portal hypertension-related complications[J].World J Gastroenterol,2014,20(45):16996-17010.
    [7]PALTSEVA EM,SEMENOVA TS,ZHIGALOVA SB,et al.Expression of plasminogen activator system components in the gastric mucosa in portal hypertensive gastropathy[J].Arkh Patol,2015,77(2):16-21.
    [8]ABBAS Z,YAKOOB J,USMAN MW,et al.Effect of Helicobacter pylori and its virulence factors on portal hypertensive gastropathy and interleukin(IL)-8,IL-10,and tumor necrosis factor-alpha levels[J].Saudi J Gastroenterol,2014,20(2):120-127.
    [9]CASAS M,CALVET X,VERGARA M,et al.Gastric vascular lesions in cirrhosis:gastropathy and antral vascular ectasia[J].Gastroenterol Hepatol,2015,38(2):97-107.
    [10]SEMEMNOVA TS,PALTSEVA EM,ZHIGALOVA SB,et al.Portal hypertensive gastropathy[J].Arkh Patol,2014,76(6):64-68.
    [11]JEON SR,KIM JO,KIM JB,et al.Portal hypertensive enteropathy diagnosed by capsule endoscopy in cirrhotic patients:a nationwide multicenter study[J].Dig Dis Sci,2014,59(5):1036-1041.
    [12]MIN YW,BAE SY,GWAK GY,et al.A clinical predictor of varices and portal hypertensive gastropathy in patients with chronic liver disease[J].Clin Mol Hepatol,2012,18(2):178-184.
    [13]CANLAS K,DOBOZI B,LIN S,et al.Using capsule endoscopy to identify GI tract lesions in cirrhotic patients with portal hypertension and chronic anemia[J].J Clin Gastroenterol,2008,42(7):844-848.
    [14]HAN S,CHAUDHARY N,WASSEF W,et al.Portal hypertensive gastropathy and gastric antral vascular ectasia[J].Curr Opin Gastroenterol,2015,31(6):506-512.
    [15]DEMACEDO GF,FERREIRA FG,RIBEIRO MA,et al.Reliability in endoscopic diagnosis of portal hypertensive gastropathy[J].World J Gastrointest Endosc,2013,5(7):323-331.
    [16]CREMERS I,RIBEIRO S.Management of variceal and nonvariceal upper gastrointestinal bleeding in patients with cirrhosis[J].Therap Adv Gastroenterol,2014,7(5):206-216.
    [17]SNYDER P,ALI R,POLES M,et al.Portal hypertensive gastropathy with a focus on management[J].Expert Rev Gastroenterol Hepatol,2015,9(9):1207-1216.
    [18]Chinese Society of Gastroenterology,Chinese Society of Hepatology and Chinese Society of Endoscopy,Chinese Medical Association.Consensus on prevention and treatment for gastroesophageal varices and variceal hemorrhage in liver cirrhosis[J].J Intern Med Concepts Pract,2009,4(2):152-158.(in Chinese)中华医学会消化病学分会,中华医学会肝病学分会,中华医学会内镜学分会.肝硬化门静脉高压食管胃静脉曲张出血的防治共识(2008,杭州)[J].内科理论与实践,2009,4(2):152-158.
    [19]CHUNG WJ.Management of portal hypertensive gastropathy and other bleeding[J].Clin Mol Hepatol,2014,20(1):1-5.
    [20]HAN X,JIANG K,WANG B,et al.Effect of rebamipide on the premalignant progression of chronic gastritis:a randomized controlled study[J].Clin Drug Investig,2015,35(10):665-673.
    [21]JING XH.Clinical efficacy of 30 patients with portal hypertensive gastropathy treated with traditonal Chinese Medicine and propranolol[J].Jiangsu J Traditi Chin Med,2010,42(3):33-34.(in Chinese)敬小华.中药联合普萘洛尔治疗门脉高压性胃病30例临床观察[J].江苏中医药,2010,42(3):33-34.
    [22]BIECKER E.Portal hypertension and gastrointestinal bleeding:diagnosis,prevention and management[J].World J Gastroenterol,2013,19(31):5035-5050.
    [23]URRUNAGA NH,ROCKEY DC.Portal hypertensive gastropathy and colopathy[J].Clin Liver Dis,2014,18(2):389-406.
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