Clinical diagnosis and treatment of hepatocellular carcinoma: From guidelines to clinical practice

Tao WANG; Dongfeng CHEN

doi:10.3969/j.issn.1001-5256.2021.08.001

Volume 37 Issue 8

Aug. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(8): 1745-1747

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Clinical diagnosis and treatment of hepatocellular carcinoma: From guidelines to clinical practice

DOI: 10.3969/j.issn.1001-5256.2021.08.001

Tao WANG,
Dongfeng CHEN^,

Department of Gastroenterology, Daping Hospital, Army Medical University, Chongqing 400042, China

Research funding:

National Natural Science Foundation of China Young Scientist Fund (82002585);

General Project of Chongqing Natural Science Foundation (cstc2020jcyj-msxmX0171)

Received Date: 2021-05-28
Accepted Date: 2021-05-28
Published Date: 2021-08-20

Abstract

Abstract

Hepatocellular carcinoma (HCC), characterized by insidious onset, rapid progression, and poor treatment outcome, is a common malignant tumor that seriously affects the health of people. Therefore, various academic research associations in China and globally have released a number of evidence-based medicine guidelines for liver cancer, focusing on the key issues in the screening, diagnosis, and treatment of HCC, and made constant updates to these guidelines. Clinicians are recommended to comprehend these guidelines with reference to their own specialties, so as to gain a better understanding of the advances in the field of liver cancer and further improve the prognosis of HCC patients.
- Carcinoma, Hepatocellular,
- Diagnosis,
- Combined Modality Therapy

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References

[1]	CHEN W, ZHENG R, BAADE PD, et al. Cancer statistics in China, 2015[J]. CA Cancer J Clin, 2016, 66(2): 115-132. DOI: 10.3322/caac.21338.
[2]	GORDAN JD, KENNEDY EB, ABOU-ALFA GK, et al. Systemic therapy for advanced hepatocellular carcinoma: ASCO guideline[J]. J Clin Oncol, 2020, 38(36): 4317-4345. DOI: 10.1200/JCO.20.02672.
[3]	Bureau of Medical AdministrationNational Health Commission of the People's Republic of China. Guidelines for diagnosis and treatment of primary liver cancer in China (2019 edition)[J]. J Clin Hepatol, 2020, 36(2): 277-292. DOI: 10.3969/j.issn.1001-5256.2020.02.007. 中华人民共和国国家卫生健康委员会医政医管局. 原发性肝癌诊疗规范(2019年版)[J]. 临床肝胆病杂志, 2020, 36(2): 277-292. DOI: 10.3969/j.issn.1001-5256.2020.02.007.
[4]	ZHOU J, YU L, GAO X, et al. Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma[J]. J Clin Oncol, 2011, 29(36): 4781-4788. DOI: 10.1200/JCO.2011.38.2697.
[5]	SUN YF, XU Y, YANG XR, et al. Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection[J]. Hepatology, 2013, 57(4): 1458-1468. DOI: 10.1002/hep.26151.
[6]	QU C, WANG Y, WANG P, et al. Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy[J]. Proc Natl Acad Sci U S A, 2019, 116(13): 6308-6312. DOI: 10.1073/pnas.1819799116.
[7]	Guidelines Working Committee of Chinese Society of Clinical Oncology. Guidelines for the diagnosis and treatment of primary liver cancer (2020 edition)[M]. Beijing: People's Medical Publishing House, 2020. 中国临床肿瘤学会指南工作委员会. 原发性肝癌诊疗指南2020[M]. 北京: 人民卫生出版社, 2020.
[8]	BI F, QIN S, GU S, et al. Donafenib versus sorafenib as first-line therapy in advanced hepatocellular carcinoma: An open-label, randomized, multicentre phase Ⅱ/Ⅲ trial[C]. Chicago, 2020 ASCO Annual Meeting Symposium: abstract 4506.
[9]	YUAN GS, HE WM, HU XY, et al. Clinical efficacy and safety analysis of camrelizumab combined with apatinib as a second-line therapy for unresectable hepatocellular carcinoma: A multicenter retrospective study[J]. Chin J Hepatol, 2021, 29(4): 326-331. DOI: 10.3760/cma.j.cn501113-20210329-00148. 袁国盛, 何伟猛, 胡晓云, 等. 卡瑞利珠单克隆抗体联合阿帕替尼二线治疗不可切除肝细胞癌的临床疗效及安全性分析: 一项多中心回顾性研究[J]. 中华肝脏病杂志, 2021, 29(4): 326-331. DOI: 10.3760/cma.j.cn501113-20210329-00148.
[10]	European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma[J]. J Hepatol, 2018, 69(1): 182-236. DOI: 10.1016/j.jhep.2018.03.019.
[11]	CALLEJA JL, CRESPO J, RINCÓN D, et al. Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort[J]. J Hepatol, 2017, 66(6): 1138-1148. DOI: 10.1016/j.jhep.2017.01.028.
[12]	MARRERO JA, KULIK LM, SIRLIN CB, et al. Diagnosis, staging, and management of hepatocellular carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases[J]. Hepatology, 2018, 68(2): 723-750. DOI: 10.1002/hep.29913.
[13]	TANG A, BASHIR MR, CORWIN MT, et al. Evidence supporting LI-RADS major features for CT-and MR imaging-based diagnosis of hepatocellular carcinoma: A systematic review[J]. Radiology, 2018, 286(1): 29-48. DOI: 10.1148/radiol.2017170554.

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Clinical diagnosis and treatment of hepatocellular carcinoma: From guidelines to clinical practice

DOI: 10.3969/j.issn.1001-5256.2021.08.001

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Clinical diagnosis and treatment of hepatocellular carcinoma: From guidelines to clinical practice

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