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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 41 Issue 2
Feb.  2025
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Article Navigation >  Journal of Clinical Hepatology  > 2025  >  41(2): 337-342

Association between Helicobacter pylori infection and hepatitis B virus-related liver diseases

DOI: 10.12449/JCH250221
  • 1.

    The First Clinical Medical College of Henan University of Chinese Medicine，Zhengzhou 450000，China

  • 2.

    Department of Hepatology and Spleen-Stomach，The First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450000，China

Research funding:

National Natural Science Foundation Youth Foundation (82104772);

The Project of Science and Technology Research in the Development Plan of Henan Province (222102310502);

Construction Project for Traditional Chinese Medicine in Henan Province (STG-ZYX02-202109);

Special Research Project of TCM in Henan Province (2022ZY2008);

Henan Province Science and Technology Research and Development Program Joint Fund (222301420062)

More Information
  • Corresponding author: MA Suping， masuping@163.com （ORCID： 0000-0002-5398-4424）
  • Received Date: 2024-06-25
  • Accepted Date: 2024-07-29
  • Published Date: 2025-02-25
    Abstract
  • As a common infectious disease in China， chronic hepatitis B is hepatocyte injury and inflammatory necrosis due to immune response caused by hepatitis B virus （HBV）. Helicobacter pylori （Hp） is a Gram-negative helicobacter that colonizes and persists in the human gastric mucosa. In recent years， an increasing number of studies have confirmed the close association between Hp infection and HBV-related liver diseases. This article reviews the articles on Hp infection and HBV-related liver diseases in recent years and discusses the association between Hp infection and HBV-related liver diseases， which shows the association between Hp infection and HBV-related liver diseases. The susceptibility to Hp in chronic hepatitis B patients increases with the progression of hepatitis B， and at the same time， Hp infection may increase the incidence rate of esophageal variceal rupture and hemorrhage and the risk of hepatic encephalopathy in patients with hepatitis B cirrhosis. Therefore， the screening and treatment of Hp infection in patients with HBV-related liver diseases should be taken seriously in clinical practice.

     

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