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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 12
Dec.  2013
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Article Contents

Research advances in noninvasive diagnosis of nonalcoholic steatohepatitis

DOI: 10.3969/j.issn.1001-5256.2013.12.007
  • Received Date: 2013-07-31
  • Published Date: 2013-12-20
  • Nonalcoholic steatohepatitis ( NASH) is a key stage in the progression of nonalcoholic fatty liver disease. Now liver biopsy is the gold standard for diagnosing NASH, but it cannot be widely used due to its invasiveness and potential hazards. Therefore, searching for noninvasive diagnostic methods for NASH with relatively high sensitivity and specificity is a hotspot of current research. The examination methods closely related to noninvasive diagnosis of NASH, such as serological tests for CK-18, TGF-β1, APRI, etc. and imaging examinations including ultrasound, TE, and MRE, are summarized. It is found that each method has advantages and disadvantages, suggesting that joint use of two or more examination methods may be the research direction for noninvasive diagnosis of NASH.

     

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