ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 12
Dec.  2013
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Article Contents

Pathogenesis and risk factors of cholesterol gallstones in patients with non- alcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2013.12.021
  • Received Date: 2013-04-18
  • Published Date: 2013-12-20
  • Epidemiological investigation suggests that the incidence of gallstones, particularly cholesterol gallstones, is high among patients with non-alcoholic fatty liver disease ( NAFLD) . NAFLD and gallstones are closely related to the diseases such as obesity, diabetes, and hyperlipidemia, so both NAFLD and gallstones are considered the manifestations of metabolic syndrome ( MS) . Many studies both at home and abroad are reviewed to investigate the pathogenesis and risk factors of cholesterol gallstones in patients with NAFLD. It is thought that the pathogenesis may be related to insulin resistance, leptin resistance, small intestinal bacterial overgrowth, etc., and age, sex, obesity, dyslipidemia, and pathoglycemia are risk factors. Understanding the pathogenesis and risk factors of cholesterol gallstones in patients with NAFLD is of great significance for the prevention and treatment of NAFLD, gallstones, and MS.


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