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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 12
Dec.  2013
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Article Contents

Role and action mechanism of 8-iso-PGF2α in traumatic liver diseases

DOI: 10.3969/j.issn.1001-5256.2013.12.022
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  • Received Date: 2013-06-19
  • Published Date: 2013-12-20
  • Oxidative stress caused by reactive oxygen species changes the function of biofilm mainly by initiating membrane lipid peroxidation and causes varying degrees of liver damage along with a series of cytokines. As the specific product of lipid peroxidation, 8-iso-PGF2α has strong bioactivity and is currently considered the gold indicator for evaluating oxidative stress and lipid peroxidation damage. The relationship between traumatic liver diseases and lipid peroxidation is summarized; 8-iso-PGF2α is recommended as a sensitive indicator of peroxidative damage in liver diseases, and its potential use in liver diseases is preliminarily discussed.

     

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