中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 9
Sep.  2016
Turn off MathJax
Article Contents

Diagnosis and treatment of hypertriglyceridemic pancreatitis in pregnancy

DOI: 10.3969/j.issn.1001-5256.2016.09.027
  • Published Date: 2016-09-20
  • Objective To investigate the clinical diagnosis and treatment of hypertriglyceridemic pancreatitis in pregnancy( HPP). Methods The clinical data of 29 patients with HPP who were admitted to Yulin Hospital of Traditional Chinese Medicine from June 2005 to June2015 were retrospectively analyzed. Results Of all the 29 patients,5( 17. 2%) were in the first trimester and 24( 82. 8%) were in the third trimester; among them,8( 27. 6%) had mild pancreatitis,14( 48. 3%) had moderate pancreatitis,and 7( 24. 1%) had severe pancreatitis. The patients had a mean serum triglyceride level of 15. 5 mmol/L. No pregnant women died; the mortality rate of the fetuses reached 17. 2%( 5/29),and all of the five cases were intrauterine fetal death. Conclusion Although the prevalence of HPP is low,its incidence rate is increasing gradually,and HPP is commonly seen in the third trimester. HPP is always associated with a high fetal mortality rate,and therefore,timely diagnosis and treatment should be provided to improve the prognosis of mother and fetus.

     

  • loading
  • [1] CHI XZ.Hyperlipidemic severe acute pancreatitis in pregnancy[J/CD].Chin J Clinicians:Electronic Edition,2012,6(1):123-125.(in Chinese)迟心左.妊娠合并高脂血症性重症急性胰腺炎[J/CD].中华临床医师杂志:电子版,2012,6(1):123-125.
    [2]HUANG GW,XIAO BH,LI YX,et al.Diagnosis and treatment of hypertriglyceridemic pancreatitis in pregnancy in 30 cases[J].J Hepatopancreatobiliary Surg,2014,26(5):376-378.(in Chinese)黄耿文,肖炳华,李宜雄,等.妊娠期高甘油三酯血症性胰腺炎30例诊治分析[J].肝胆胰外科杂志,2014,26(5):376-378.
    [3]JIA WQ,WU CF,YIN B.Clinical diagnosis and treatment of 21patients with hyperlipidemic acute pancreatitis[J].China J Prac Med,2012,39(4):23-26.(in Chinese)贾万奇,吴成甫,尹泊.高甘油三酯血症性急性胰腺炎21例临床诊治分析[J].中国实用医刊,2012,39(4):23-26.
    [4] Pancreatic Surgery Group of Surgery Branch of Chinese Medical Association.Guidelines for the diagnosis and treatment of acute pancreatitis(2014 edition)[J].Chin J Dig Surg,2014,14(1):1-5.(in Chinese)中华医学会消化病学分会胰腺疾病学组.中国急性胰腺炎诊治指南(2014版)[J].中华消化外科杂志,2014,14(1):1-5.
    [5]LI ZT,CUI XY,LIU X.Application of plasma exchange in treatment of severe hyperlipidemic acute pancreatitis[J].Mod Dig Int,2014,19(2):102-104.(in Chinese)李兆滔,崔西玉,刘欣.血浆置换在治疗重症高脂血症性急性胰腺炎中的应用[J].现代消化及介入诊疗,2014,19(2):102-104.
    [6]LIU Y,LYU WS,WANG L,et al.Lipoprotein lipase gene mutation in one patient with recurrent acute pancreatitis in pregnancy caused by hypertriglyceridemia[J].Chin J Intern Med,2015,54(3):220-222.(in Chinese)刘营,吕文山,王娈,等.高甘油三酯血症致妊娠期反复发生急性胰腺炎患者脂蛋白脂肪酶基因突变一例[J].中华内科杂志,2015,54(3):220-222.
    [7]TAN DY,XU JY.Therapeutic effect of bedside plasma exchange in treatment of severe hyperlipidemic acute pancreatitis[J].J Pract Med,2012,28(11):1832-1834.(in Chinese)谈定玉,徐继扬.床边血浆置换治疗重症高脂血症性急性胰腺炎疗效观察[J].实用医学杂志,2012,28(11):1832-1834.
    [8]LI Z,WU LL.Diagnosis and treatment of hypertriglyceridemic acute pancreatitis in late pregnancy[J].Chin J Emerg Med,2015,24(11):1283-1284.(in Chinese)李振,吴林林.晚期妊娠合并高甘油三酯血症急性胰腺炎诊治分析[J].中华急诊医学杂志,2015,24(11):1283-1284.
    [9]LIU KM.Analysis of clinical diagnosis and treatment of hypertriglyceridemia-induced acute pancreatitis in 9 cases[J].China Mod Med,2012,19(27):35-36.(in Chinese)刘开明.高甘油三酯血症性急性胰腺炎9例临床诊治分析[J].中国当代医学,2012,19(27):35-36.
    [10]SUN J,WANG YX.Effect of serum triglyceride level on conditions in patients with acute pancreatitis:an analysis of 313 cases[J].Fujian Med J,2011,33(1):74-76.(in Chinese)孙娟,王耀新.血甘油三酯水平对313例急性胰腺炎病情影响的观察[J].福建医药杂志,2011,33(1):74-76.
    [11] WANG L,ZHANG QX,WANG QL.Psychological nursing and health education for patients with hyperlipidemic acute pancreatitis[J].Med Inf,2010,23(6):190-190.(in Chinese)王莉,张巧仙,王庆兰.高脂血症性急性胰腺炎的心理护理及健康教育[J].医学信息,2010,23(6):190-190.
    [12] WANG XY,ZENG XC,XIAO Y,et al.Effect of hypertriglyceridemia on serum TNF-a and IL-6 in rats with acute necrotizing pancreatitis[J].J Clin Res,2012,29(10):1847-1850.(in Chinese)王湘英,曾晓晨,肖彦,等.高甘油三脂血症对急性坏死性胰腺炎大鼠TNF-α、IL-6的影响[J].医学临床研究,2012,29(10):1847-1850.
    [13]KAN LH,HONG JW,CAI ZR,et al.One case of recurrent acute pancreatitis caused by hypertriglyceridemia[J].Chin Foreign Med Res,2012,10(9):137-137.(in Chinese)阚丽虹,洪家旺,蔡振荣,等.高甘油三酯血症反复诱发急性胰腺炎1例[J].中外医学研究,2012,10(9):137-137.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1584) PDF downloads(397) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return