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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 12
Dec.  2020
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Article Contents

Diagnosis and treatment of easily misdiagnosed hepatic sclerosing hemangioma

DOI: 10.3969/j.issn.1001-5256.2020.12.043
Research funding:

 

  • Received Date: 2020-05-27
  • Published Date: 2020-12-20
  • Hepatic sclerosing hemangioma( HSH) is a rare benign tumor that is considered fibrosis and hyaline change caused by degenerative changes of cavernous angioma,and changes in pathological features cause the changes in imaging features,making this atypical hemangioma easily misdiagnosed as primary or metastatic malignant tumor. Although there are many studies on the imaging findings of this disease,it is still difficult to diagnose and most patients underwent resection since it is misdiagnosed as malignant tumor. There is still a low rate of confirmed diagnosis before surgery. This article elaborates on the etiology,clinical manifestations and pathological features,imaging findings,diagnosis,and treatment of HSH,in order to provide a reference for the diagnosis and treatment of this disease.

     

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  • [1] DIETRICH CF,MERTENS JC,BRADEN B,et al. Contrastenhanced ultrasound of histologically proven liver hemangiomas[J]. Hepatology,2007,45(5):1139-1145.
    [2] CASEIRO-ALVES F,BRITO J,ARAUJO AE,et al. Liver haemangioma:Common and uncommon findings and how to improve the differential diagnosis[J]. Eur Radiol,2007,17(6):1544-1554.
    [3] International Hepato-Pancreato-Biliary Association,China Branch,Hepatic Hemangioma Professional Committee. Multidisciplinary expert consensus on the diagnosis and treatment of hepatic hemangioma(2019 edition)[J]. J Clin Hepatol,2019,35(9):1928-1932.(in Chinese)国际肝胆胰协会中国分会肝血管瘤专业委员会.肝血管瘤诊断和治疗多学科专家共识(2019版)[J].临床肝胆病杂志,2019,35(9):1928-1932.
    [4] MAKHLOUF HR,ISHAK KG. Sclerosed hemangioma and sclerosing cavernous hemangioma of the liver:A comparative clinicopathologic and immunohistochemical study with emphasis on the role of mast cells in their histogenesis[J]. Liver,2002,22(1):70-78.
    [5] SHEPHERD NA,LEE G. Solitary necrotic nodules of the liver simulating hepatic metastases[J]. J Clin Pathol,1983,36(10):1181-1183.
    [6] CHENG HC,TSAI SH,CHIANG JH,et al. Hyalinized liver hemangioma mimicking malignant tumor at MR imaging[J]. AJR Am J Roentgenol,1995,165(4):1016-1017.
    [7] OKANO H,SHIRAKI K,INOUE H,et al. Natural course of cavernous hepatic hemangioma[J]. Oncol Rep,2001,8(2):411-414.
    [8] BURT A,PORTMANN B,FERRELL L. MacSween’s pathology of the liver[M]. 6th ed,Philadelphia,PA:Elsevier,2012:761-851.
    [9] BAJENARU N,BALABAN V,SVULESCU F,et al. Hepatic hemangioma-review[J]. J Med Life,2015,8(Spec Issue):4-11.
    [10] SHIMADA Y,TAKAHASHI Y,IGUCHI H,et al. A hepatic sclerosed hemangioma with significant morphological change over a period of 10 years:A case report[J]. J Med Case Rep,2013,7:139.
    [11] YUKI M,EMOTO Y,KINOSHITA Y,et al. Sclerosed hemangioma accompanied by multiple cavernous hemangiomas of the liver[J]. Am J Case Rep,2015,16:401-405.
    [12] NUNES L,MELLO-AMOEDO CD,YAMAUCHI FI,et al. Atypical hepatic hemangioma:Imaging features of hyalinized hemangioma[J]. Einstein(Sao Paulo),2018,16(2):e AI4256.
    [13] SHIMADA Y,TAKAHASHI Y,IGUCHI H,et al. A hepatic sclerosed hemangioma with significant morphological change over a period of 10 years:A case report[J]. J Med Case Rep,2013,7:139.
    [14] WAKASUGI M,UESHIMA S,TEI M,et al. Multiple hepatic sclerosing hemangioma mimicking metastatic liver tumor successfully treated by laparoscopic surgery:Report of a case[J]. Int J Surg Case Rep,2015,8C:137-140.
    [15] MATHIEU D,RAHMOUNI A,VASILE N,et al. Sclerosed liver hemangioma mimicking malignant tumor at MR imaging:Pathologic correlation[J]. J Magn Reson Imaging,1994,4(3):506-508.
    [16] CHANG SD,STUNELL H. A pictorial review of the MRI appearances of focal liver lesions[J]. J Med Imaging Radiat Sci,2010,41(4):180-195.
    [17] VILGRAIN V,BOULOS L,VULLIERME MP,et al. Imaging of atypical hemangiomas of the liver with pathologic correlation[J]. Radiographics,2000,20(2):379-397.
    [18] BEHBAHANI S,HOFFMANN JC,STONEBRIDGE R,et al. Clinical case report:Sclerosing hemangioma of the liver,a rare but great mimicker[J]. Radiol Case Rep,2016,11(2):58-61.
    [19] LEE VT,MAGNAYE M,TAN HW,et al. Sclerosing haemangioma mimicking hepatocellular carcinoma[J]. Singapore Med J,2005,46(3):140-143.
    [20] SUGO H,SEKINE Y,MIYANO S,et al. Hepatic sclerosing hemangioma with predominance of the sclerosed area mimicking a biliary cystadenocarcinoma[J]. Case Reports Hepatol,2018,2018:7353170.
    [21] MORI H,IKEGAMI T,IMURA S,et al. Sclerosed hemangioma of the liver:Report of a case and review of the literature[J].Hepatol Res,2008,38(5):529-533.
    [22] DOYLE DJ,KHALILI K,GUINDI M,et al. Imaging features of sclerosed hemangioma[J]. AJR Am J Roentgenol,2007,189(1):67-72.
    [23] MIYAMOTO S,OSHITA A,DAIMARU Y,et al. Hepatic sclerosed hemangioma:A case report and review of the literature[J]. BMC Surg,2015,15:45.
    [24] ANDEEN NK,BHARGAVA P,PARK JO,et al. Cavernous hemangioma with extensive sclerosis masquerading as intrahepatic cholangiocarcinoma-A pathologist’s perspective[J].Radiol Case Rep,2014,9(2):937.
    [25] HO CL,CHEN S,YEUNG DW,et al. Dual-tracer PET/CT imaging in evaluation of metastatic hepatocellular carcinoma[J]. J Nucl Med,2007,48(6):902-909.
    [26] RIDGE CA,SHIA J,GERST SR,et al. Sclerosed hemangioma of the liver:Concordance of MRI features with histologic characteristics[J]. J Magn Reson Imaging,2014,39(4):812-818.
    [27] HIDA T,NISHIE A,TAJIMA T,et al. Sclerosed hemangioma of the liver:Possible diagnostic value of diffusion-weighted magnetic resonance imaging[J]. Jpn J Radiol,2010,28(3):235-238.
    [28] MIYATA T,BEPPU T,KURAMOTO K,et al. Hepatic sclerosed hemangioma with special attention to diffusion-weighted magnetic resonance imaging[J]. Surg Case Rep,2018,4(1):3.
    [29] SHIN YM. Sclerosing hemangioma in the liver[J]. Korean J Hepatol,2011,17(3):242-246.
    [30] WANG C,MIAO R,LIU H,et al. Intrahepatic biliary cystadenoma and cystadenocarcinoma:An experience of 30 cases[J]. Dig Liver Dis,2012,44(5):426-431.
    [31] HORSMANS Y,LAKA A,GIGOT JF,et al. Serum and cystic fluid CA 19-9 determinations as a diagnostic help in liver cysts of uncertain nature[J]. Liver,1996,16(4):255-257.
    [32] POJCHAMARNWIPUTH S,NA CHIANGMAI W,CHOTIROSNIRAMIT A,et al. Computed tomography of biliary cystadenoma and biliary cystadenocarcinoma[J]. Singapore Med J,2008,49(5):392-396.
    [33] MAMONE G,di PIAZZA A,CAROLLO V,et al. Imaging of primary malignant tumors in non-cirrhotic liver[J]. Diagn Interv Imaging,2020.[Online ahead of print]
    [34] KOYAMA R,MINAGAWA N,MAEDA Y,et al. A hepatic sclerosing hemangioma emerged in the postoperative course of multiple gastric carcinoid tumors masquerading as metachronous liver metastasis[J]. Int J Surg Case Rep,2019,58:1-5.
    [35] RYDER SD,British Society of Gastroenterology. Guidelines for the diagnosis and treatment of hepatocellular carcinoma(HCC)in adults[J]. Gut,2003,52(Suppl 3):iii1-iii8.
    [36] XU L,YANG X,KE S,et al. Resection as first-line therapy for large hepatic sclerosing hemangioma:A case report[J].Onco Targets Ther,2019,12:6839-6842.
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